SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2atp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8D_A_CLWA906_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 2atp T-CELL SURFACE
GLYCOPROTEIN CD8
ALPHA CHAIN
(Mus
musculus) 		4 / 5 PRO A   5
VAL A  32
TYR A 111
MET A 110
 None
 1.33A 1m8dA-2atpA:
0.0		 1m8dA-2atpA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8D_B_CLWB907_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 2atp T-CELL SURFACE
GLYCOPROTEIN CD8
ALPHA CHAIN
(Mus
musculus) 		4 / 5 PRO A   5
VAL A  32
TYR A 111
MET A 110
 None
 1.33A 1m8dB-2atpA:
0.0		 1m8dB-2atpA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M9J_A_CLWA906_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 2atp T-CELL SURFACE
GLYCOPROTEIN CD8
ALPHA CHAIN
(Mus
musculus) 		4 / 5 PRO A   5
VAL A  32
TYR A 111
MET A 110
 None
 1.24A 1m9jA-2atpA:
0.0		 1m9jA-2atpA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M9J_B_CLWB907_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 2atp T-CELL SURFACE
GLYCOPROTEIN CD8
ALPHA CHAIN
(Mus
musculus) 		4 / 5 PRO A   5
VAL A  32
TYR A 111
MET A 110
 None
 1.23A 1m9jB-2atpA:
undetectable		 1m9jB-2atpA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 2atp T-CELL SURFACE
GLYCOPROTEIN CD8
ALPHA CHAIN
(Mus
musculus) 		5 / 10 VAL A 116
PHE A 101
GLN A  41
LEU A  89
LEU A  24
 None
 1.05A 3gwxA-2atpA:
undetectable		 3gwxA-2atpA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2atp T-CELL SURFACE
GLYCOPROTEIN CD8
BETA CHAIN
(Mus
musculus) 		4 / 6 GLU B  89
ASP B  90
ASP B  92
ARG B  35
 None
 1.24A 4kcnA-2atpB:
undetectable		 4kcnA-2atpB:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2atp T-CELL SURFACE
GLYCOPROTEIN CD8
BETA CHAIN
(Mus
musculus) 		4 / 6 GLU B  89
ASP B  90
ASP B  92
ARG B  35
 None
 1.28A 4kcnB-2atpB:
undetectable		 4kcnB-2atpB:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2atp T-CELL SURFACE
GLYCOPROTEIN CD8
ALPHA CHAIN
(Mus
musculus) 		4 / 6 LYS A  68
LEU A  69
PHE A  75
LEU A  74
 None
 1.17A 5x19P-2atpA:
undetectable		 5x19P-2atpA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_B_SAMB505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 2atp T-CELL SURFACE
GLYCOPROTEIN CD8
ALPHA CHAIN
T-CELL SURFACE
GLYCOPROTEIN CD8
BETA CHAIN
(Mus
musculus;
Mus
musculus) 		5 / 12 LYS B 103
GLY B 100
ILE A 105
TYR B  32
LEU A  39
 None
 1.09A 6bp4B-2atpB:
undetectable		 6bp4B-2atpB:
15.56