SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2atz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 2atz H. PYLORI PREDICTED
CODING REGION HP0184
(Helicobacter
pylori) 		3 / 3 ASP A  12
SER A  14
ARG A  67
 None
 0.97A 3loqA-2atzA:
undetectable		 3loqA-2atzA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 2atz H. PYLORI PREDICTED
CODING REGION HP0184
(Helicobacter
pylori) 		5 / 10 TYR A  78
ASP A  77
PRO A 143
ALA A 139
GLY A  80
 None
DGT  A 201 (-2.9A)
None
None
None
 1.34A 4mmdA-2atzA:
undetectable		 4mmdA-2atzA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 2atz H. PYLORI PREDICTED
CODING REGION HP0184
(Helicobacter
pylori) 		3 / 3 THR A 103
HIS A 118
ASN A 101
 None
 0.83A 5n4tA-2atzA:
undetectable		 5n4tA-2atzA:
19.17