SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2aua'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 2aua HYPOTHETICAL PROTEIN
(Bacillus
cereus) 		4 / 8 ARG A  93
TYR A 168
GLU A  90
HIS A  30
 None
 0.93A 1nx9A-2auaA:
undetectable		 1nx9A-2auaA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 2aua HYPOTHETICAL PROTEIN
(Bacillus
cereus) 		4 / 8 ARG A  93
TYR A 168
GLU A  90
HIS A  30
 None
 0.91A 1nx9B-2auaA:
undetectable		 1nx9B-2auaA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 2aua HYPOTHETICAL PROTEIN
(Bacillus
cereus) 		4 / 8 ARG A  93
TYR A 168
GLU A  90
HIS A  30
 None
 0.91A 1nx9C-2auaA:
undetectable		 1nx9C-2auaA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 2aua HYPOTHETICAL PROTEIN
(Bacillus
cereus) 		4 / 8 ARG A  93
TYR A 168
GLU A  90
HIS A  30
 None
 0.92A 1nx9D-2auaA:
undetectable		 1nx9D-2auaA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 2aua HYPOTHETICAL PROTEIN
(Bacillus
cereus) 		5 / 12 ILE A  11
ALA A 116
ALA A   8
ILE A 182
PHE A 123
 None
 1.09A 3gwsX-2auaA:
undetectable		 3gwsX-2auaA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 2aua HYPOTHETICAL PROTEIN
(Bacillus
cereus) 		5 / 12 ILE A  11
ALA A 116
ALA A   8
ILE A 182
PHE A 123
 None
 1.16A 4lnwA-2auaA:
undetectable		 4lnwA-2auaA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 2aua HYPOTHETICAL PROTEIN
(Bacillus
cereus) 		5 / 12 ILE A  11
ALA A 116
ALA A   8
ILE A 182
PHE A 123
 None
 1.17A 4lnxA-2auaA:
undetectable		 4lnxA-2auaA:
20.94