SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2auc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KTV_A_ADNA403_1 (S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2)	2auc	MYOSIN A TAIL INTERACTING PROTEIN (Plasmodium knowlesi)	5 / 12	SER A 97 ASP A 117 ASP A 111 ILE A 115 ILE A 93	None	1.45A	4ktvA-2aucA: undetectable 4ktvB-2aucA: 0.0	4ktvA-2aucA: 15.23 4ktvB-2aucA: 15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KTV_C_ADNC403_1 (S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2)	2auc	MYOSIN A TAIL INTERACTING PROTEIN (Plasmodium knowlesi)	5 / 11	SER A 97 ASP A 117 ASP A 111 ILE A 115 ILE A 93	None	1.32A	4ktvC-2aucA: undetectable 4ktvD-2aucA: undetectable	4ktvC-2aucA: 15.23 4ktvD-2aucA: 15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FBP_B_ADNB404_0 (S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2)	2auc	MYOSIN A TAIL INTERACTING PROTEIN (Plasmodium knowlesi)	5 / 12	ASP A 111 ILE A 115 ILE A 93 SER A 97 ASP A 117	None	1.28A	6fbpA-2aucA: undetectable 6fbpB-2aucA: undetectable	6fbpA-2aucA: 18.18 6fbpB-2aucA: 18.18

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4KTV_A_ADNA403_1","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2;S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","2auc","MYOSIN A TAIL INTERACTING PROTEIN","Plasmodium knowlesi",5,"SER A  97;ASP A 117;ASP A 111;ILE A 115;ILE A  93","None","1.45A","4ktvA-2aucA:undetectable;4ktvB-2aucA:0.0","4ktvA-2aucA:15.23;4ktvB-2aucA:15.23"],["4KTV_C_ADNC403_1","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2;S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","2auc","MYOSIN A TAIL INTERACTING PROTEIN","Plasmodium knowlesi",5,"SER A  97;ASP A 117;ASP A 111;ILE A 115;ILE A  93","None","1.32A","4ktvC-2aucA:undetectable;4ktvD-2aucA:undetectable","4ktvC-2aucA:15.23;4ktvD-2aucA:15.23"],["6FBP_B_ADNB404_0","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","2auc","MYOSIN A TAIL INTERACTING PROTEIN","Plasmodium knowlesi",5,"ASP A 111;ILE A 115;ILE A  93;SER A  97;ASP A 117","None","1.28A","6fbpA-2aucA:undetectable;6fbpB-2aucA:undetectable","6fbpA-2aucA:18.18;6fbpB-2aucA:18.18"]]