SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2aug'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C12_C_SPMC1434_1 (NITROALKANE OXIDASE)	2aug	GROWTH FACTOR RECEPTOR-BOUND PROTEIN 14 (Homo sapiens)	5 / 12	LEU A 527 LEU A 464 SER A 478 LEU A 477 VAL A 476	None	1.24A	2c12C-2augA: undetectable	2c12C-2augA: 15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABL_C_CHDC271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	2aug	GROWTH FACTOR RECEPTOR-BOUND PROTEIN 14 (Homo sapiens)	4 / 5	GLN A 489 PHE A 488 LEU A 516 PHE A 510	None	1.23A	3ablC-2augA: undetectable 3ablJ-2augA: undetectable	3ablC-2augA: 18.68 3ablJ-2augA: 17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1B_C_CHDC306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2aug	GROWTH FACTOR RECEPTOR-BOUND PROTEIN 14 (Homo sapiens)	4 / 6	GLN A 489 PHE A 488 LEU A 516 PHE A 510	None	1.10A	5b1bC-2augA: undetectable 5b1bJ-2augA: undetectable	5b1bC-2augA: 18.68 5b1bJ-2augA: 17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NMP_C_CHDC307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2aug	GROWTH FACTOR RECEPTOR-BOUND PROTEIN 14 (Homo sapiens)	4 / 6	GLN A 489 PHE A 488 LEU A 516 PHE A 510	None	1.29A	6nmpC-2augA: undetectable 6nmpJ-2augA: undetectable	6nmpC-2augA: 18.68 6nmpJ-2augA: 17.36

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2C12_C_SPMC1434_1","NITROALKANE OXIDASE","2aug","GROWTH FACTOR RECEPTOR-BOUND PROTEIN 14","Homo sapiens",5,"LEU A 527;LEU A 464;SER A 478;LEU A 477;VAL A 476","None","1.24A","2c12C-2augA:undetectable","2c12C-2augA:15.01"],["3ABL_C_CHDC271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","2aug","GROWTH FACTOR RECEPTOR-BOUND PROTEIN 14","Homo sapiens",4,"GLN A 489;PHE A 488;LEU A 516;PHE A 510","None","1.23A","3ablC-2augA:undetectable;3ablJ-2augA:undetectable","3ablC-2augA:18.68;3ablJ-2augA:17.36"],["5B1B_C_CHDC306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2aug","GROWTH FACTOR RECEPTOR-BOUND PROTEIN 14","Homo sapiens",4,"GLN A 489;PHE A 488;LEU A 516;PHE A 510","None","1.10A","5b1bC-2augA:undetectable;5b1bJ-2augA:undetectable","5b1bC-2augA:18.68;5b1bJ-2augA:17.36"],["6NMP_C_CHDC307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2aug","GROWTH FACTOR RECEPTOR-BOUND PROTEIN 14","Homo sapiens",4,"GLN A 489;PHE A 488;LEU A 516;PHE A 510","None","1.29A","6nmpC-2augA:undetectable;6nmpJ-2augA:undetectable","6nmpC-2augA:18.68;6nmpJ-2augA:17.36"]]