SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2auw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 2auw HYPOTHETICAL PROTEIN
NE0471
(Nitrosomonas
europaea) 		3 / 3 ALA A  85
VAL A  32
TRP A  80
 None
None
GOL  A1202 (-3.4A)
 0.93A 1tkqA-2auwA:
undetectable		 1tkqA-2auwA:
6.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2auw HYPOTHETICAL PROTEIN
NE0471
(Nitrosomonas
europaea) 		5 / 10 LEU A  38
ILE A  37
VAL A  32
ALA A  81
PHE A  72
 None
GOL  A1202 (-3.4A)
None
None
None
 1.04A 1xp0A-2auwA:
undetectable		 1xp0A-2auwA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_A_LURA201_1
(TRANSTHYRETIN)		 2auw HYPOTHETICAL PROTEIN
NE0471
(Nitrosomonas
europaea) 		3 / 3 LYS A  82
LEU A  30
ALA A  85
 None
 0.78A 4iizA-2auwA:
undetectable		 4iizA-2auwA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_A_IMNA201_1
(TRANSTHYRETIN)		 2auw HYPOTHETICAL PROTEIN
NE0471
(Nitrosomonas
europaea) 		3 / 3 LYS A  82
LEU A  30
ALA A  85
 None
 0.64A 4ikiA-2auwA:
undetectable		 4ikiA-2auwA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)		 2auw HYPOTHETICAL PROTEIN
NE0471
(Nitrosomonas
europaea) 		3 / 3 ARG A  21
PHE A  72
LEU A   9
 None
 0.84A 5veuA-2auwA:
undetectable		 5veuA-2auwA:
14.81