SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2av9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2201_1
(PROTEIN (METHIONINE
REPRESSOR))		 2av9 THIOESTERASE
(Pseudomonas
aeruginosa) 		4 / 4 HIS A  30
ALA A  77
PHE A  78
GLY A  29
 None
 1.19A 1mj2B-2av9A:
undetectable		 1mj2B-2av9A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_1
(PROTEIN (METHIONINE
REPRESSOR))		 2av9 THIOESTERASE
(Pseudomonas
aeruginosa) 		4 / 4 HIS A  30
ALA A  77
PHE A  78
GLY A  29
 None
 1.16A 1mj2D-2av9A:
undetectable		 1mj2D-2av9A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_A_SAMA199_1
(METHIONINE REPRESSOR)		 2av9 THIOESTERASE
(Pseudomonas
aeruginosa) 		4 / 4 HIS A  30
ALA A  77
PHE A  78
GLY A  29
 None
 1.16A 1mjoB-2av9A:
undetectable		 1mjoB-2av9A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_B_SAMB200_0
(METHIONINE REPRESSOR)		 2av9 THIOESTERASE
(Pseudomonas
aeruginosa) 		4 / 4 HIS A  30
ALA A  77
PHE A  78
GLY A  29
 None
 1.10A 1mjoA-2av9A:
undetectable		 1mjoA-2av9A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_D_SAMD200_1
(METHIONINE REPRESSOR)		 2av9 THIOESTERASE
(Pseudomonas
aeruginosa) 		4 / 4 HIS A  30
ALA A  77
PHE A  78
GLY A  29
 None
 1.17A 1mjoD-2av9A:
undetectable		 1mjoD-2av9A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2av9 THIOESTERASE
(Pseudomonas
aeruginosa) 		4 / 5 ARG A   6
PHE A  73
LEU A 102
ALA A  74
 None
 1.43A 2e1qD-2av9A:
undetectable		 2e1qD-2av9A:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 2av9 THIOESTERASE
(Pseudomonas
aeruginosa) 		5 / 12 ASP A  24
ALA A  38
ILE A  18
ARG A  21
ASN A  32
 None
 1.10A 2ejtA-2av9A:
undetectable		 2ejtA-2av9A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2av9 THIOESTERASE
(Pseudomonas
aeruginosa) 		5 / 12 VAL A  31
GLN A  16
THR A  42
ILE A  82
PHE A  39
 None
 1.31A 2vdyA-2av9A:
undetectable		 2vdyA-2av9A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2av9 THIOESTERASE
(Pseudomonas
aeruginosa) 		5 / 12 TYR A  98
LEU A  86
ILE A  18
HIS A 118
LEU A  54
 None
 1.41A 2xkwA-2av9A:
undetectable		 2xkwA-2av9A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)		 2av9 THIOESTERASE
(Pseudomonas
aeruginosa) 		4 / 7 TYR A  98
ARG A  90
GLY A 114
ASP A  71
 None
 0.92A 2y05A-2av9A:
undetectable
2y05B-2av9A:
undetectable		 2y05A-2av9A:
16.57
2y05B-2av9A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 2av9 THIOESTERASE
(Pseudomonas
aeruginosa) 		3 / 3 TYR A  36
VAL A  76
THR A  35
 None
 0.69A 2ygnA-2av9A:
undetectable		 2ygnA-2av9A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2av9 THIOESTERASE
(Pseudomonas
aeruginosa) 		5 / 12 VAL A  31
GLN A  16
THR A  42
ILE A  82
PHE A  39
 None
 1.34A 4c49B-2av9A:
undetectable		 4c49B-2av9A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2av9 THIOESTERASE
(Pseudomonas
aeruginosa) 		5 / 12 VAL A  31
GLN A  16
THR A  42
ILE A  82
PHE A  39
 None
 1.28A 4c49C-2av9A:
undetectable		 4c49C-2av9A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2av9 THIOESTERASE
(Pseudomonas
aeruginosa) 		5 / 12 VAL A  31
GLN A  16
THR A  42
ILE A  82
PHE A  39
 None
 1.25A 4c49D-2av9A:
undetectable		 4c49D-2av9A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 2av9 THIOESTERASE
(Pseudomonas
aeruginosa) 		5 / 10 MET A  84
ILE A  18
VAL A  76
ASP A  24
PHE A  39
 None
 1.49A 6b4yA-2av9A:
undetectable		 6b4yA-2av9A:
19.56