SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2avu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 2avu FLAGELLAR
TRANSCRIPTIONAL
ACTIVATOR FLHC
(Escherichia
coli) 		3 / 3 PRO E 113
GLU E 104
TYR E 102
 None
 0.75A 2zmbA-2avuE:
undetectable		 2zmbA-2avuE:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2avu FLAGELLAR
TRANSCRIPTIONAL
ACTIVATOR FLHC
(Escherichia
coli) 		3 / 3 GLY E  55
PRO E  52
LEU E  26
 None
 0.60A 3hcpB-2avuE:
2.1		 3hcpB-2avuE:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 2avu FLAGELLAR
TRANSCRIPTIONAL
ACTIVATOR FLHC
(Escherichia
coli) 		4 / 5 TYR E 102
GLY E 112
TYR E  99
GLY E  23
 None
 0.93A 5ayfA-2avuE:
undetectable		 5ayfA-2avuE:
19.55