SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2avx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B6R_B_CRNB603_1 (CREATINE KINASE B-TYPE)	2avx	REGULATORY PROTEIN SDIA (Escherichia coli)	4 / 6	THR A 120 VAL A 119 LEU A 133 GLU A 31	None	1.07A	3b6rB-2avxA: undetectable	3b6rB-2avxA: 19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3H5G_B_LEIB16_0 (COIL SER L16D-PEN)	2avx	REGULATORY PROTEIN SDIA (Escherichia coli)	4 / 5	LEU A 133 LYS A 153 GLN A 155 LEU A 157	None	0.92A	3h5gA-2avxA: undetectable 3h5gB-2avxA: undetectable	3h5gA-2avxA: 9.47 3h5gB-2avxA: 9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3H5G_C_LEIC16_0 (COIL SER L16D-PEN)	2avx	REGULATORY PROTEIN SDIA (Escherichia coli)	4 / 6	LEU A 133 LYS A 153 GLN A 155 LEU A 157	None	1.00A	3h5gB-2avxA: undetectable 3h5gC-2avxA: undetectable	3h5gB-2avxA: 9.47 3h5gC-2avxA: 9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UDC_A_DEXA1778_2 (GLUCOCORTICOID RECEPTOR)	2avx	REGULATORY PROTEIN SDIA (Escherichia coli)	3 / 3	MET A 154 GLN A 35 TYR A 42	None	1.05A	4udcA-2avxA: undetectable	4udcA-2avxA: 19.10

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3B6R_B_CRNB603_1","CREATINE KINASE B-TYPE","2avx","REGULATORY PROTEIN SDIA","Escherichia coli",4,"THR A 120;VAL A 119;LEU A 133;GLU A  31","None","1.07A","3b6rB-2avxA:undetectable","3b6rB-2avxA:19.22"],["3H5G_B_LEIB16_0","COIL SER L16D-PEN","2avx","REGULATORY PROTEIN SDIA","Escherichia coli",4,"LEU A 133;LYS A 153;GLN A 155;LEU A 157","None","0.92A","3h5gA-2avxA:undetectable;3h5gB-2avxA:undetectable","3h5gA-2avxA:9.47;3h5gB-2avxA:9.47"],["3H5G_C_LEIC16_0","COIL SER L16D-PEN","2avx","REGULATORY PROTEIN SDIA","Escherichia coli",4,"LEU A 133;LYS A 153;GLN A 155;LEU A 157","None","1.00A","3h5gB-2avxA:undetectable;3h5gC-2avxA:undetectable","3h5gB-2avxA:9.47;3h5gC-2avxA:9.47"],["4UDC_A_DEXA1778_2","GLUCOCORTICOID RECEPTOR","2avx","REGULATORY PROTEIN SDIA","Escherichia coli",3,"MET A 154;GLN A  35;TYR A  42","None","1.05A","4udcA-2avxA:undetectable","4udcA-2avxA:19.10"]]