SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2aw0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C6Y_B_MK1B524_1 (PROTEIN (PROTEASE))	2aw0	MENKES COPPER-TRANSPORTING ATPASE (Homo sapiens)	5 / 11	LEU A 70 ALA A 68 ILE A 21 THR A 5 ILE A 7	None	0.95A	1c6yA-2aw0A: undetectable	1c6yA-2aw0A: 24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S8F_B_BEZB1503_0 (RAS-RELATED PROTEIN RAB-9A)	2aw0	MENKES COPPER-TRANSPORTING ATPASE (Homo sapiens)	4 / 6	VAL A 45 THR A 5 LEU A 57 ARG A 58	None	1.07A	1s8fB-2aw0A: undetectable	1s8fB-2aw0A: 18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KW4_A_TICA600_1 (CYTOCHROME P450 2B4)	2aw0	MENKES COPPER-TRANSPORTING ATPASE (Homo sapiens)	6 / 11	ILE A 61 ILE A 34 SER A 33 GLU A 4 THR A 5 VAL A 31	None	1.40A	3kw4A-2aw0A: undetectable	3kw4A-2aw0A: 12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOU_A_C04A207_1 (UNCHARACTERIZED PROTEIN)	2aw0	MENKES COPPER-TRANSPORTING ATPASE (Homo sapiens)	3 / 3	GLY A 43 GLU A 4 THR A 5	None	0.37A	4kouA-2aw0A: undetectable	4kouA-2aw0A: 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NJT_D_017D101_1 (PROTEASE)	2aw0	MENKES COPPER-TRANSPORTING ATPASE (Homo sapiens)	5 / 11	LEU A 70 ALA A 68 ILE A 21 THR A 5 ILE A 7	None	0.95A	4njtC-2aw0A: undetectable	4njtC-2aw0A: 21.43

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1C6Y_B_MK1B524_1","PROTEIN (PROTEASE);PROTEIN (PROTEASE)","2aw0","MENKES COPPER-TRANSPORTING ATPASE","Homo sapiens",5,"LEU A  70;ALA A  68;ILE A  21;THR A   5;ILE A   7","None","0.95A","1c6yA-2aw0A:undetectable","1c6yA-2aw0A:24.49"],["1S8F_B_BEZB1503_0","RAS-RELATED PROTEIN RAB-9A","2aw0","MENKES COPPER-TRANSPORTING ATPASE","Homo sapiens",4,"VAL A  45;THR A   5;LEU A  57;ARG A  58","None","1.07A","1s8fB-2aw0A:undetectable","1s8fB-2aw0A:18.64"],["3KW4_A_TICA600_1","CYTOCHROME P450 2B4","2aw0","MENKES COPPER-TRANSPORTING ATPASE","Homo sapiens",6,"ILE A  61;ILE A  34;SER A  33;GLU A   4;THR A   5;VAL A  31","None","1.40A","3kw4A-2aw0A:undetectable","3kw4A-2aw0A:12.92"],["4KOU_A_C04A207_1","UNCHARACTERIZED PROTEIN","2aw0","MENKES COPPER-TRANSPORTING ATPASE","Homo sapiens",3,"GLY A  43;GLU A   4;THR A   5","None","0.37A","4kouA-2aw0A:undetectable","4kouA-2aw0A:18.75"],["4NJT_D_017D101_1","PROTEASE;PROTEASE","2aw0","MENKES COPPER-TRANSPORTING ATPASE","Homo sapiens",5,"LEU A  70;ALA A  68;ILE A  21;THR A   5;ILE A   7","None","0.95A","4njtC-2aw0A:undetectable","4njtC-2aw0A:21.43"]]