SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2aw2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_D_W9TD506_1 (HEMOLYTIC LECTIN CEL-III)	2aw2	B AND T LYMPHOCYTE ATTENUATOR TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14 (Homo sapiens)	4 / 5	GLU B 31 GLY B 30 TYR A 39 GLN A 37	None	1.30A	3w9tD-2aw2B: undetectable	3w9tD-2aw2B: 13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_E_W9TE505_1 (HEMOLYTIC LECTIN CEL-III)	2aw2	B AND T LYMPHOCYTE ATTENUATOR TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14 (Homo sapiens)	4 / 5	GLU B 31 GLY B 30 TYR A 39 GLN A 37	None	1.28A	3w9tE-2aw2B: undetectable	3w9tE-2aw2B: 13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_G_W9TG505_1 (HEMOLYTIC LECTIN CEL-III)	2aw2	B AND T LYMPHOCYTE ATTENUATOR TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14 (Homo sapiens)	4 / 5	GLU B 31 GLY B 30 TYR A 39 GLN A 37	None	1.34A	3w9tG-2aw2B: undetectable	3w9tG-2aw2B: 13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YMG_A_SAMA1001_1 (PUTATIVE SAM-DEPENDENT O-METHYLTRANFERASE)	2aw2	B AND T LYMPHOCYTE ATTENUATOR TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14 (Homo sapiens; Homo sapiens)	4 / 4	SER A 112 SER A 128 GLU A 125 ASP B 7	None	1.38A	4ymgA-2aw2A: undetectable	4ymgA-2aw2A: 17.72

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3W9T_D_W9TD506_1","HEMOLYTIC LECTIN CEL-III","2aw2","B AND T LYMPHOCYTE ATTENUATOR;TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14","Homo sapiens",4,"GLU B  31;GLY B  30;TYR A  39;GLN A  37","None","1.30A","3w9tD-2aw2B:undetectable","3w9tD-2aw2B:13.27"],["3W9T_E_W9TE505_1","HEMOLYTIC LECTIN CEL-III","2aw2","B AND T LYMPHOCYTE ATTENUATOR;TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14","Homo sapiens",4,"GLU B  31;GLY B  30;TYR A  39;GLN A  37","None","1.28A","3w9tE-2aw2B:undetectable","3w9tE-2aw2B:13.27"],["3W9T_G_W9TG505_1","HEMOLYTIC LECTIN CEL-III","2aw2","B AND T LYMPHOCYTE ATTENUATOR;TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14","Homo sapiens",4,"GLU B  31;GLY B  30;TYR A  39;GLN A  37","None","1.34A","3w9tG-2aw2B:undetectable","3w9tG-2aw2B:13.27"],["4YMG_A_SAMA1001_1","PUTATIVE SAM-DEPENDENT O-METHYLTRANFERASE","2aw2","B AND T LYMPHOCYTE ATTENUATOR;TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14","Homo sapiens;Homo sapiens",4,"SER A 112;SER A 128;GLU A 125;ASP B   7","None","1.38A","4ymgA-2aw2A:undetectable","4ymgA-2aw2A:17.72"]]