SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2awf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_A_IBPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2awf UBIQUITIN-CONJUGATIN
G ENZYME E2 G1
(Homo
sapiens) 		5 / 10 VAL A  22
VAL A 117
GLY A  28
ALA A  27
LEU A  17
 None
 1.10A 4ph9A-2awfA:
undetectable		 4ph9A-2awfA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_B_IBPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2awf UBIQUITIN-CONJUGATIN
G ENZYME E2 G1
(Homo
sapiens) 		5 / 10 VAL A  22
VAL A 117
GLY A  28
ALA A  27
LEU A  17
 None
 1.09A 4ph9B-2awfA:
undetectable		 4ph9B-2awfA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FDY_U_DB8U302_1
(-)		 2awf UBIQUITIN-CONJUGATIN
G ENZYME E2 G1
(Homo
sapiens) 		5 / 9 LEU A  59
VAL A  40
SER A 126
LEU A 128
ILE A  42
 None
 1.32A 6fdyU-2awfA:
undetectable		 6fdyU-2awfA:
18.12