SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2axo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)		 2axo HYPOTHETICAL PROTEIN
ATU2684
(Agrobacterium
fabrum) 		5 / 11 TYR A 104
VAL A  74
GLY A  75
ALA A 235
LEU A 237
 None
 1.16A 2bxgA-2axoA:
undetectable		 2bxgA-2axoA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA451_1
(CYTOCHROME P450
164A2)		 2axo HYPOTHETICAL PROTEIN
ATU2684
(Agrobacterium
fabrum) 		5 / 10 ALA A 249
LEU A 108
LEU A 120
ILE A 119
ALA A 118
 None
 1.03A 3r9cA-2axoA:
undetectable		 3r9cA-2axoA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 2axo HYPOTHETICAL PROTEIN
ATU2684
(Agrobacterium
fabrum) 		4 / 4 LEU A 120
ILE A  68
TYR A  78
TYR A 135
 None
 1.45A 3vt7A-2axoA:
undetectable		 3vt7A-2axoA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2axo HYPOTHETICAL PROTEIN
ATU2684
(Agrobacterium
fabrum) 		4 / 8 ASP A 130
ILE A 134
GLY A 133
VAL A  73
 None
 0.74A 4acbB-2axoA:
2.2
4acbC-2axoA:
2.3		 4acbB-2axoA:
19.96
4acbC-2axoA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_1
(PROTEASE)		 2axo HYPOTHETICAL PROTEIN
ATU2684
(Agrobacterium
fabrum) 		5 / 8 ALA A 172
VAL A 251
GLY A 214
PRO A 151
VAL A 152
 None
 1.24A 4ll3A-2axoA:
undetectable		 4ll3A-2axoA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_2
(PROTEASE)		 2axo HYPOTHETICAL PROTEIN
ATU2684
(Agrobacterium
fabrum) 		5 / 9 ALA A 172
VAL A 251
GLY A 214
PRO A 151
VAL A 152
 None
 1.24A 4ll3B-2axoA:
undetectable		 4ll3B-2axoA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2axo HYPOTHETICAL PROTEIN
ATU2684
(Agrobacterium
fabrum) 		4 / 6 TYR A 114
ASP A 124
HIS A 125
ILE A 134
 None
 1.24A 5ih0A-2axoA:
undetectable		 5ih0A-2axoA:
20.32