SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2axp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2axp HYPOTHETICAL PROTEIN
BSU20280
(Bacillus
subtilis) 		3 / 3 ILE A 128
LEU A 131
VAL A 135
 None
 0.40A 1mz9B-2axpA:
undetectable		 1mz9B-2axpA:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 2axp HYPOTHETICAL PROTEIN
BSU20280
(Bacillus
subtilis) 		4 / 6 ASP A  10
ILE A 108
LEU A 129
GLU A 121
 None
 0.98A 2ya7A-2axpA:
undetectable		 2ya7A-2axpA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 2axp HYPOTHETICAL PROTEIN
BSU20280
(Bacillus
subtilis) 		4 / 6 ASP A  10
ILE A 108
LEU A 129
GLU A 121
 None
 0.97A 2ya7B-2axpA:
undetectable		 2ya7B-2axpA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 2axp HYPOTHETICAL PROTEIN
BSU20280
(Bacillus
subtilis) 		4 / 6 ASP A  10
ILE A 108
LEU A 129
GLU A 121
 None
 0.96A 2ya7D-2axpA:
undetectable		 2ya7D-2axpA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GLM_A_ACTA613_0
(GLYCOSIDE HYDROLASE
FAMILY 43)		 2axp HYPOTHETICAL PROTEIN
BSU20280
(Bacillus
subtilis) 		3 / 3 ASP A  10
SER A  66
TYR A  70
 None
 0.86A 5glmA-2axpA:
undetectable		 5glmA-2axpA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZP_A_CFFA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 2axp HYPOTHETICAL PROTEIN
BSU20280
(Bacillus
subtilis) 		5 / 9 ILE A  60
VAL A  64
MET A 136
LEU A 141
ILE A  92
 None
 1.38A 5mzpA-2axpA:
undetectable		 5mzpA-2axpA:
19.15