SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2aym'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 2aym U1 SMALL NUCLEAR
RIBONUCLEOPROTEIN A
(Drosophila
melanogaster) 		3 / 3 ASN A   8
ALA A  81
LYS A  82
 None
 0.99A 3runA-2aymA:
undetectable		 3runA-2aymA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 2aym U1 SMALL NUCLEAR
RIBONUCLEOPROTEIN A
(Drosophila
melanogaster) 		3 / 3 GLU A  19
THR A  73
HIS A  74
 None
 0.81A 4q15A-2aymA:
undetectable		 4q15A-2aymA:
10.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 2aym U1 SMALL NUCLEAR
RIBONUCLEOPROTEIN A
(Drosophila
melanogaster) 		3 / 3 GLU A  19
THR A  73
HIS A  74
 None
 0.83A 4q15B-2aymA:
undetectable		 4q15B-2aymA:
10.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)		 2aym U1 SMALL NUCLEAR
RIBONUCLEOPROTEIN A
(Drosophila
melanogaster) 		5 / 12 LEU A  28
ASN A  15
VAL A  50
ALA A  48
ILE A  78
 None
 1.16A 4x1kD-2aymA:
undetectable		 4x1kD-2aymA:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 2aym U1 SMALL NUCLEAR
RIBONUCLEOPROTEIN A
(Drosophila
melanogaster) 		3 / 3 GLU A  19
THR A  73
HIS A  74
 None
 0.79A 4ydqB-2aymA:
undetectable		 4ydqB-2aymA:
11.52