SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2azn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 2azn PUTATIVE
5-AMINO-6-(5-PHOSPHO
RIBOSYLAMINO)URACIL
REDUCTASE
(Methanocaldococc
us
jannaschii) 		4 / 5 GLY A 156
HIS A  42
ASP A  97
ASP A  61
 NAP  A2001 (-3.3A)
None
None
NAP  A2001 (-3.1A)
 0.93A 2oxtB-2aznA:
undetectable		 2oxtB-2aznA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 2azn PUTATIVE
5-AMINO-6-(5-PHOSPHO
RIBOSYLAMINO)URACIL
REDUCTASE
(Methanocaldococc
us
jannaschii) 		3 / 3 GLY A  56
GLY A 155
GLY A  54
 NAP  A2001 (-3.2A)
NAP  A2001 (-4.2A)
NAP  A2001 (-3.1A)
 0.37A 3bogC-2aznA:
undetectable		 3bogC-2aznA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)		 2azn PUTATIVE
5-AMINO-6-(5-PHOSPHO
RIBOSYLAMINO)URACIL
REDUCTASE
(Methanocaldococc
us
jannaschii) 		4 / 7 ILE A  79
LYS A 133
LYS A 165
GLY A 162
 None
None
None
NAP  A2001 ( 3.7A)
 1.12A 3sj0X-2aznA:
undetectable		 3sj0X-2aznA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 2azn PUTATIVE
5-AMINO-6-(5-PHOSPHO
RIBOSYLAMINO)URACIL
REDUCTASE
(Methanocaldococc
us
jannaschii) 		4 / 6 LEU A 159
ASN A 160
LEU A 168
VAL A 222
 NAP  A2001 (-4.8A)
None
None
None
 1.10A 4okbA-2aznA:
undetectable		 4okbA-2aznA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 2azn PUTATIVE
5-AMINO-6-(5-PHOSPHO
RIBOSYLAMINO)URACIL
REDUCTASE
(Methanocaldococc
us
jannaschii) 		5 / 12 ILE A 151
LEU A 139
GLU A 154
ARG A  78
GLY A  50
 None
 1.24A 5k7uA-2aznA:
undetectable		 5k7uA-2aznA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 2azn PUTATIVE
5-AMINO-6-(5-PHOSPHO
RIBOSYLAMINO)URACIL
REDUCTASE
(Methanocaldococc
us
jannaschii) 		3 / 3 LYS A   7
LEU A 139
ILE A 148
 None
 0.71A 5kc0A-2aznA:
undetectable		 5kc0A-2aznA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 2azn PUTATIVE
5-AMINO-6-(5-PHOSPHO
RIBOSYLAMINO)URACIL
REDUCTASE
(Methanocaldococc
us
jannaschii) 		3 / 3 LYS A   7
LEU A 139
ILE A 148
 None
 0.76A 5kc4A-2aznA:
undetectable		 5kc4A-2aznA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 2azn PUTATIVE
5-AMINO-6-(5-PHOSPHO
RIBOSYLAMINO)URACIL
REDUCTASE
(Methanocaldococc
us
jannaschii) 		5 / 10 VAL A 134
GLY A 130
GLU A 106
ALA A 103
LEU A 139
 NAP  A2001 (-4.0A)
None
None
None
None
 1.01A 5x6yB-2aznA:
undetectable		 5x6yB-2aznA:
14.02