SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2azo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		 2azo MUTH
(Escherichia
coli) 		4 / 8 PRO A 146
GLU A 150
GLU A 156
ASP A 157
 None
 1.21A 1dtlA-2azoA:
undetectable		 1dtlA-2azoA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)		 2azo MUTH
(Escherichia
coli) 		3 / 3 PHE A 217
LEU A 154
LEU A 117
 None
 0.66A 1mx1E-2azoA:
undetectable		 1mx1E-2azoA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_B_BEZB1503_0
(RAS-RELATED PROTEIN
RAB-9A)		 2azo MUTH
(Escherichia
coli) 		4 / 6 VAL A 106
THR A 107
GLU A 109
ARG A 114
 None
 1.13A 1s8fB-2azoA:
undetectable		 1s8fB-2azoA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 2azo MUTH
(Escherichia
coli) 		3 / 3 ARG A   5
ILE A  57
TRP A  58
 None
 1.13A 2nodB-2azoA:
undetectable		 2nodB-2azoA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2azo MUTH
(Escherichia
coli) 		3 / 3 ARG A   5
ILE A  57
TRP A  58
 None
 0.97A 3nw2A-2azoA:
undetectable		 3nw2A-2azoA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2azo MUTH
(Escherichia
coli) 		3 / 3 ARG A   5
ILE A  57
TRP A  58
 None
 1.03A 3nw2B-2azoA:
undetectable		 3nw2B-2azoA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 2azo MUTH
(Escherichia
coli) 		4 / 6 LEU A 221
LEU A 142
LEU A  17
GLU A  77
 None
 0.91A 5tudD-2azoA:
undetectable		 5tudD-2azoA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_A_TRPA403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 2azo MUTH
(Escherichia
coli) 		4 / 8 ARG A 184
THR A  93
ILE A  81
PRO A  82
 None
 1.06A 6a4iA-2azoA:
undetectable		 6a4iA-2azoA:
21.55