SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2azp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 2azp HYPOTHETICAL PROTEIN
PA1268
(Pseudomonas
aeruginosa) 		3 / 3 SER A 128
THR A  11
PHE A  78
 None
 0.75A 2x91A-2azpA:
undetectable		 2x91A-2azpA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E4E_B_4PZB501_1
(CYTOCHROME P450 2E1)		 2azp HYPOTHETICAL PROTEIN
PA1268
(Pseudomonas
aeruginosa) 		3 / 3 ALA A  62
THR A  16
CYH A  88
 None
 0.72A 3e4eB-2azpA:
undetectable		 3e4eB-2azpA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 2azp HYPOTHETICAL PROTEIN
PA1268
(Pseudomonas
aeruginosa) 		6 / 12 GLY A  91
VAL A 119
GLY A 161
PRO A 286
THR A 287
VAL A 131
 None
 1.35A 3el5B-2azpA:
undetectable		 3el5B-2azpA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2azp HYPOTHETICAL PROTEIN
PA1268
(Pseudomonas
aeruginosa) 		4 / 5 PRO A 283
THR A 114
VAL A 116
GLY A 117
 None
 0.92A 3elzA-2azpA:
undetectable		 3elzA-2azpA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 2azp HYPOTHETICAL PROTEIN
PA1268
(Pseudomonas
aeruginosa) 		4 / 8 GLY A  22
PHE A  23
ILE A   7
PHE A  79
 None
 0.94A 3ko0O-2azpA:
undetectable
3ko0Q-2azpA:
undetectable		 3ko0O-2azpA:
14.24
3ko0Q-2azpA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 2azp HYPOTHETICAL PROTEIN
PA1268
(Pseudomonas
aeruginosa) 		6 / 12 ILE A 288
GLY A  89
GLY A 237
LEU A 244
THR A  11
ASP A 232
 None
 1.49A 4e3aA-2azpA:
undetectable		 4e3aA-2azpA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 2azp HYPOTHETICAL PROTEIN
PA1268
(Pseudomonas
aeruginosa) 		6 / 12 ILE A 288
GLY A  89
GLY A 237
LEU A 244
THR A  11
ASP A 232
 None
 1.49A 4e3aB-2azpA:
undetectable		 4e3aB-2azpA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_B_NCTB501_1
(CYTOCHROME P450 2A6)		 2azp HYPOTHETICAL PROTEIN
PA1268
(Pseudomonas
aeruginosa) 		4 / 7 PHE A 269
VAL A 131
GLY A  94
THR A  16
 None
 0.81A 4ejjB-2azpA:
undetectable		 4ejjB-2azpA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_A_ACTA401_0
(UNCHARACTERIZED
PROTEIN)		 2azp HYPOTHETICAL PROTEIN
PA1268
(Pseudomonas
aeruginosa) 		6 / 9 GLY A  89
ASP A 232
SER A 234
CYH A 236
GLY A 237
THR A 238
 None
 0.34A 4lb0A-2azpA:
41.2		 4lb0A-2azpA:
29.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UW0_A_SAMA1506_0
(WBDD)		 2azp HYPOTHETICAL PROTEIN
PA1268
(Pseudomonas
aeruginosa) 		5 / 12 TYR A 185
ALA A 188
GLN A 190
ILE A 198
ILE A 157
 None
 1.03A 4uw0A-2azpA:
undetectable		 4uw0A-2azpA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)		 2azp HYPOTHETICAL PROTEIN
PA1268
(Pseudomonas
aeruginosa) 		5 / 12 CYH A 246
LEU A 247
LEU A 166
ALA A 136
ALA A 158
 None
 1.15A 4x1kD-2azpA:
undetectable		 4x1kD-2azpA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 2azp HYPOTHETICAL PROTEIN
PA1268
(Pseudomonas
aeruginosa) 		5 / 12 VAL A 119
ALA A 121
PHE A 269
ILE A  93
ASN A 133
 None
 1.03A 5hgcA-2azpA:
undetectable		 5hgcA-2azpA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 2azp HYPOTHETICAL PROTEIN
PA1268
(Pseudomonas
aeruginosa) 		5 / 12 VAL A 119
ALA A 121
THR A 240
ILE A  93
ASN A 133
 None
 1.41A 5hgcA-2azpA:
undetectable		 5hgcA-2azpA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 2azp HYPOTHETICAL PROTEIN
PA1268
(Pseudomonas
aeruginosa) 		5 / 12 ILE A 198
VAL A 189
VAL A 167
GLY A 239
THR A 238
 None
 1.22A 5igiA-2azpA:
undetectable		 5igiA-2azpA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 2azp HYPOTHETICAL PROTEIN
PA1268
(Pseudomonas
aeruginosa) 		4 / 6 ILE A  93
GLY A 160
ASN A 162
ILE A 288
 None
 0.91A 5j4nB-2azpA:
undetectable		 5j4nB-2azpA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 2azp HYPOTHETICAL PROTEIN
PA1268
(Pseudomonas
aeruginosa) 		4 / 6 GLY A 160
THR A 238
SER A 241
GLY A 237
 None
 0.87A 5k4pA-2azpA:
undetectable		 5k4pA-2azpA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2azp HYPOTHETICAL PROTEIN
PA1268
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  90
THR A  11
ASP A 232
GLY A  94
PHE A 269
 None
 1.46A 5m66B-2azpA:
undetectable		 5m66B-2azpA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 2azp HYPOTHETICAL PROTEIN
PA1268
(Pseudomonas
aeruginosa) 		5 / 12 ASN A  80
SER A 234
THR A  11
GLY A 237
THR A 238
 None
 1.07A 5oj0A-2azpA:
undetectable		 5oj0A-2azpA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 2azp HYPOTHETICAL PROTEIN
PA1268
(Pseudomonas
aeruginosa) 		5 / 6 LEU A  64
VAL A  76
THR A 114
LEU A  18
LEU A  59
 None
 1.28A 5tudD-2azpA:
undetectable		 5tudD-2azpA:
20.68