SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2azw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1W5U_B_DVAB8_0 (GRAMICIDIN D)	2azw	MUTT/NUDIX FAMILY PROTEIN (Enterococcus faecalis)	3 / 3	VAL A 102 VAL A 25 TRP A 143	None	0.93A	1w5uA-2azwA: undetectable 1w5uB-2azwA: undetectable	1w5uA-2azwA: 7.26 1w5uB-2azwA: 7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K37_A_BCZA468_0 (NEURAMINIDASE)	2azw	MUTT/NUDIX FAMILY PROTEIN (Enterococcus faecalis)	5 / 12	ARG A 18 GLU A 49 ARG A 90 GLU A 66 ARG A 62	None	1.34A	3k37A-2azwA: undetectable	3k37A-2azwA: 15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K37_A_BCZA468_0 (NEURAMINIDASE)	2azw	MUTT/NUDIX FAMILY PROTEIN (Enterococcus faecalis)	5 / 12	GLU A 49 ARG A 90 GLU A 66 GLU A 63 ARG A 62	None	1.50A	3k37A-2azwA: undetectable	3k37A-2azwA: 15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K39_I_BCZI1001_0 (NEURAMINIDASE)	2azw	MUTT/NUDIX FAMILY PROTEIN (Enterococcus faecalis)	5 / 12	ARG A 18 GLU A 49 ARG A 90 GLU A 66 ARG A 62	None	1.41A	3k39I-2azwA: undetectable	3k39I-2azwA: 15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPN_B_ZMRB700_1 (NEURAMINIDASE)	2azw	MUTT/NUDIX FAMILY PROTEIN (Enterococcus faecalis)	5 / 12	ARG A 18 GLU A 49 ARG A 90 GLU A 66 ARG A 62	None	1.36A	4cpnB-2azwA: undetectable	4cpnB-2azwA: 15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGZ_B_CQAB302_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE)	2azw	MUTT/NUDIX FAMILY PROTEIN (Enterococcus faecalis)	4 / 8	GLU A 57 GLU A 58 ARG A 62 GLY A 48	None	0.99A	4fgzA-2azwA: undetectable 4fgzB-2azwA: undetectable	4fgzA-2azwA: 18.66 4fgzB-2azwA: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M2V_A_BZ1A302_2 (CARBONIC ANHYDRASE 2)	2azw	MUTT/NUDIX FAMILY PROTEIN (Enterococcus faecalis)	3 / 3	HIS A 120 VAL A 140 LEU A 131	None	0.74A	4m2vA-2azwA: undetectable	4m2vA-2azwA: 19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZBR_A_ACTA608_0 (SERUM ALBUMIN)	2azw	MUTT/NUDIX FAMILY PROTEIN (Enterococcus faecalis)	3 / 3	LYS A 132 ARG A 133 HIS A 136	None	1.24A	4zbrA-2azwA: undetectable	4zbrA-2azwA: 12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L17_A_ZMRA512_1 (NEURAMINIDASE)	2azw	MUTT/NUDIX FAMILY PROTEIN (Enterococcus faecalis)	5 / 12	ARG A 18 GLU A 49 ARG A 90 GLU A 66 ARG A 62	None	1.39A	5l17A-2azwA: undetectable	5l17A-2azwA: 17.26

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1W5U_B_DVAB8_0","GRAMICIDIN D","2azw","MUTT\/NUDIX FAMILY PROTEIN","Enterococcus faecalis",3,"VAL A 102;VAL A  25;TRP A 143","None","0.93A","1w5uA-2azwA:undetectable;1w5uB-2azwA:undetectable","1w5uA-2azwA:7.26;1w5uB-2azwA:7.26"],["3K37_A_BCZA468_0","NEURAMINIDASE","2azw","MUTT\/NUDIX FAMILY PROTEIN","Enterococcus faecalis",5,"ARG A  18;GLU A  49;ARG A  90;GLU A  66;ARG A  62","None","1.34A","3k37A-2azwA:undetectable","3k37A-2azwA:15.58"],["3K37_A_BCZA468_0","NEURAMINIDASE","2azw","MUTT\/NUDIX FAMILY PROTEIN","Enterococcus faecalis",5,"GLU A  49;ARG A  90;GLU A  66;GLU A  63;ARG A  62","None","1.50A","3k37A-2azwA:undetectable","3k37A-2azwA:15.58"],["3K39_I_BCZI1001_0","NEURAMINIDASE","2azw","MUTT\/NUDIX FAMILY PROTEIN","Enterococcus faecalis",5,"ARG A  18;GLU A  49;ARG A  90;GLU A  66;ARG A  62","None","1.41A","3k39I-2azwA:undetectable","3k39I-2azwA:15.83"],["4CPN_B_ZMRB700_1","NEURAMINIDASE","2azw","MUTT\/NUDIX FAMILY PROTEIN","Enterococcus faecalis",5,"ARG A  18;GLU A  49;ARG A  90;GLU A  66;ARG A  62","None","1.36A","4cpnB-2azwA:undetectable","4cpnB-2azwA:15.88"],["4FGZ_B_CQAB302_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE","2azw","MUTT\/NUDIX FAMILY PROTEIN","Enterococcus faecalis",4,"GLU A  57;GLU A  58;ARG A  62;GLY A  48","None","0.99A","4fgzA-2azwA:undetectable;4fgzB-2azwA:undetectable","4fgzA-2azwA:18.66;4fgzB-2azwA:18.66"],["4M2V_A_BZ1A302_2","CARBONIC ANHYDRASE 2","2azw","MUTT\/NUDIX FAMILY PROTEIN","Enterococcus faecalis",3,"HIS A 120;VAL A 140;LEU A 131","None","0.74A","4m2vA-2azwA:undetectable","4m2vA-2azwA:19.54"],["4ZBR_A_ACTA608_0","SERUM ALBUMIN","2azw","MUTT\/NUDIX FAMILY PROTEIN","Enterococcus faecalis",3,"LYS A 132;ARG A 133;HIS A 136","None","1.24A","4zbrA-2azwA:undetectable","4zbrA-2azwA:12.11"],["5L17_A_ZMRA512_1","NEURAMINIDASE","2azw","MUTT\/NUDIX FAMILY PROTEIN","Enterococcus faecalis",5,"ARG A  18;GLU A  49;ARG A  90;GLU A  66;ARG A  62","None","1.39A","5l17A-2azwA:undetectable","5l17A-2azwA:17.26"]]