SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2b06'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_N_TRPN1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	2b06	MUTT/NUDIX FAMILY PROTEIN (Streptococcus pneumoniae)	5 / 9	GLY A 64 ILE A 15 VAL A 24 VAL A 108 GLN A 26	None None None None MG A 300 ( 4.6A)	1.43A	3fi0N-2b06A: undetectable	3fi0N-2b06A: 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_B_PCFB1802_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	2b06	MUTT/NUDIX FAMILY PROTEIN (Streptococcus pneumoniae)	4 / 7	THR A 63 VAL A 108 PRO A 41 ILE A 12	None	1.07A	5vkqA-2b06A: undetectable 5vkqB-2b06A: undetectable	5vkqA-2b06A: 6.44 5vkqB-2b06A: 6.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_C_PCFC1803_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	2b06	MUTT/NUDIX FAMILY PROTEIN (Streptococcus pneumoniae)	4 / 8	THR A 63 VAL A 108 PRO A 41 ILE A 12	None	1.06A	5vkqB-2b06A: undetectable 5vkqC-2b06A: undetectable	5vkqB-2b06A: 6.44 5vkqC-2b06A: 6.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_D_PCFD1803_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	2b06	MUTT/NUDIX FAMILY PROTEIN (Streptococcus pneumoniae)	4 / 7	THR A 63 VAL A 108 PRO A 41 ILE A 12	None	1.08A	5vkqC-2b06A: undetectable 5vkqD-2b06A: undetectable	5vkqC-2b06A: 6.44 5vkqD-2b06A: 6.44

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3FI0_N_TRPN1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","2b06","MUTT\/NUDIX FAMILY PROTEIN","Streptococcus pneumoniae",5,"GLY A  64;ILE A  15;VAL A  24;VAL A 108;GLN A  26","None;None;None;None; MG A 300 ( 4.6A)","1.43A","3fi0N-2b06A:undetectable","3fi0N-2b06A:18.75"],["5VKQ_B_PCFB1802_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","2b06","MUTT\/NUDIX FAMILY PROTEIN","Streptococcus pneumoniae",4,"THR A  63;VAL A 108;PRO A  41;ILE A  12","None","1.07A","5vkqA-2b06A:undetectable;5vkqB-2b06A:undetectable","5vkqA-2b06A:6.44;5vkqB-2b06A:6.44"],["5VKQ_C_PCFC1803_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","2b06","MUTT\/NUDIX FAMILY PROTEIN","Streptococcus pneumoniae",4,"THR A  63;VAL A 108;PRO A  41;ILE A  12","None","1.06A","5vkqB-2b06A:undetectable;5vkqC-2b06A:undetectable","5vkqB-2b06A:6.44;5vkqC-2b06A:6.44"],["5VKQ_D_PCFD1803_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","2b06","MUTT\/NUDIX FAMILY PROTEIN","Streptococcus pneumoniae",4,"THR A  63;VAL A 108;PRO A  41;ILE A  12","None","1.08A","5vkqC-2b06A:undetectable;5vkqD-2b06A:undetectable","5vkqC-2b06A:6.44;5vkqD-2b06A:6.44"]]