SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2b0h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		 2b0h TALIN-1
(Mus
musculus) 		4 / 6 LEU A1968
LEU A1965
ILE A1916
ARG A1919
 None
 0.70A 2rlfA-2b0hA:
undetectable
2rlfB-2b0hA:
undetectable		 2rlfA-2b0hA:
20.37
2rlfB-2b0hA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		 2b0h TALIN-1
(Mus
musculus) 		4 / 6 LEU A1968
LEU A1965
ILE A1916
ARG A1919
 None
 0.78A 2rlfC-2b0hA:
undetectable
2rlfD-2b0hA:
undetectable		 2rlfC-2b0hA:
20.37
2rlfD-2b0hA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2b0h TALIN-1
(Mus
musculus) 		4 / 5 ARG A1859
MET A1857
THR A1860
LEU A1896
 None
 1.37A 5w97J-2b0hA:
undetectable		 5w97J-2b0hA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2b0h TALIN-1
(Mus
musculus) 		4 / 7 ALA A1861
THR A1860
ILE A1916
VAL A1964
 None
 0.94A 6cduF-2b0hA:
6.6
6cduJ-2b0hA:
6.5		 6cduF-2b0hA:
19.62
6cduJ-2b0hA:
19.62