SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2b0r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_1
(HIV-II PROTEASE)		 2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN
(Cryptosporidium
parvum) 		5 / 12 ILE A  94
VAL A  87
ILE A 103
ILE A 115
ILE A 113
 None
 0.87A 1hshA-2b0rA:
undetectable		 1hshA-2b0rA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN
(Cryptosporidium
parvum) 		4 / 8 GLY A 108
ILE A 128
VAL A 129
PRO A 130
 None
 0.92A 1rxcB-2b0rA:
undetectable		 1rxcB-2b0rA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN
(Cryptosporidium
parvum) 		4 / 7 GLY A 108
ILE A 128
VAL A 129
PRO A 130
 None
 1.02A 1rxcC-2b0rA:
undetectable		 1rxcC-2b0rA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN
(Cryptosporidium
parvum) 		4 / 7 GLY A 108
ILE A 128
VAL A 129
PRO A 130
 None
 0.99A 1rxcD-2b0rA:
undetectable		 1rxcD-2b0rA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN
(Cryptosporidium
parvum) 		4 / 8 GLY A 108
ILE A 128
VAL A 129
PRO A 130
 None
 0.95A 1rxcE-2b0rA:
undetectable		 1rxcE-2b0rA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN
(Cryptosporidium
parvum) 		4 / 7 GLY A 108
ILE A 128
VAL A 129
PRO A 130
 None
 0.91A 1rxcF-2b0rA:
undetectable		 1rxcF-2b0rA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN
(Cryptosporidium
parvum) 		4 / 8 GLY A 108
ILE A 128
VAL A 129
PRO A 130
 None
 0.94A 1rxcI-2b0rA:
undetectable		 1rxcI-2b0rA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN
(Cryptosporidium
parvum) 		4 / 8 GLY A 108
ILE A 128
VAL A 129
PRO A 130
 None
 0.90A 1rxcK-2b0rA:
undetectable		 1rxcK-2b0rA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN
(Cryptosporidium
parvum) 		4 / 7 GLY A 108
ILE A 128
VAL A 129
PRO A 130
 None
 0.92A 1rxcL-2b0rA:
undetectable		 1rxcL-2b0rA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN
(Cryptosporidium
parvum) 		4 / 7 SER A 111
SER A 112
SER A  93
ASN A  92
 None
 1.15A 2cmlA-2b0rA:
undetectable		 2cmlA-2b0rA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN
(Cryptosporidium
parvum) 		4 / 8 SER A 111
SER A 112
SER A  93
ASN A  92
 None
 1.06A 2cmlB-2b0rA:
undetectable		 2cmlB-2b0rA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN
(Cryptosporidium
parvum) 		4 / 8 SER A 111
SER A 112
SER A  93
ASN A  92
 None
 1.11A 2cmlC-2b0rA:
undetectable		 2cmlC-2b0rA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN
(Cryptosporidium
parvum) 		4 / 8 SER A 111
SER A 112
SER A  93
ASN A  92
 None
 1.14A 2cmlD-2b0rA:
undetectable		 2cmlD-2b0rA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_1
(PROTEASE)		 2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN
(Cryptosporidium
parvum) 		5 / 9 ILE A  94
VAL A  87
ILE A 103
ILE A 115
ILE A 113
 None
 0.74A 3s43A-2b0rA:
undetectable		 3s43A-2b0rA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN
(Cryptosporidium
parvum) 		4 / 5 THR A  39
GLY A  41
PRO A  43
ASN A  56
 None
 1.03A 3u8qA-2b0rA:
undetectable		 3u8qA-2b0rA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN
(Cryptosporidium
parvum) 		4 / 7 ILE A  85
ILE A  94
GLU A  68
VAL A  45
 None
 0.80A 3ua5B-2b0rA:
undetectable		 3ua5B-2b0rA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN
(Cryptosporidium
parvum) 		4 / 8 GLY A 108
ILE A 128
VAL A 129
PRO A 130
 None
 0.95A 4e1vA-2b0rA:
undetectable		 4e1vA-2b0rA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN
(Cryptosporidium
parvum) 		4 / 7 GLY A 108
ILE A 128
VAL A 129
PRO A 130
 None
 0.93A 4e1vB-2b0rA:
undetectable		 4e1vB-2b0rA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN
(Cryptosporidium
parvum) 		4 / 8 GLY A 108
ILE A 128
VAL A 129
PRO A 130
 None
 0.93A 4e1vC-2b0rA:
undetectable		 4e1vC-2b0rA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN
(Cryptosporidium
parvum) 		4 / 8 GLY A 108
ILE A 128
VAL A 129
PRO A 130
 None
 0.95A 4e1vD-2b0rA:
undetectable		 4e1vD-2b0rA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN
(Cryptosporidium
parvum) 		4 / 8 GLY A 108
ILE A 128
VAL A 129
PRO A 130
 None
 0.94A 4e1vE-2b0rA:
undetectable		 4e1vE-2b0rA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN
(Cryptosporidium
parvum) 		4 / 8 GLY A 108
ILE A 128
VAL A 129
PRO A 130
 None
 0.97A 4e1vH-2b0rA:
undetectable		 4e1vH-2b0rA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA601_1
(SERUM ALBUMIN)		 2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN
(Cryptosporidium
parvum) 		5 / 12 VAL A  91
ASN A  73
LEU A  47
VAL A  87
LEU A  66
 None
 1.46A 4po0A-2b0rA:
undetectable		 4po0A-2b0rA:
15.84