SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2b0v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 2b0v NUDIX HYDROLASE
(Nitrosomonas
europaea) 		5 / 10 ILE A  46
ASN A   6
ALA A  49
GLU A  53
ARG A  52
 None
None
None
EDO  A 201 (-3.3A)
None
 1.24A 3u6tA-2b0vA:
undetectable		 3u6tA-2b0vA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 2b0v NUDIX HYDROLASE
(Nitrosomonas
europaea) 		4 / 8 VAL A  91
ILE A  13
SER A  51
ALA A  10
 None
 0.95A 4eyzA-2b0vA:
undetectable		 4eyzA-2b0vA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 2b0v NUDIX HYDROLASE
(Nitrosomonas
europaea) 		4 / 8 VAL A  91
ILE A  13
SER A  51
ALA A  10
 None
 0.95A 4eyzB-2b0vA:
undetectable		 4eyzB-2b0vA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_1
(SIALIDASE)		 2b0v NUDIX HYDROLASE
(Nitrosomonas
europaea) 		5 / 12 ARG A 139
GLU A  65
GLU A  14
ASP A  17
TYR A 134
 None
 1.34A 6ekuA-2b0vA:
undetectable		 6ekuA-2b0vA:
11.51