SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2b1n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 2b1n SPE31
(Pachyrhizus
erosus) 		3 / 3 ALA A  34
VAL A 173
TRP A   8
 None
 0.99A 1c4dA-2b1nA:
undetectable
1c4dB-2b1nA:
undetectable		 1c4dA-2b1nA:
4.27
1c4dB-2b1nA:
4.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 2b1n SPE31
(Pachyrhizus
erosus) 		5 / 8 ASP A 156
ASP A 146
ILE A 202
ILE A 200
GLY A 152
 None
NAG  A 600 (-3.5A)
None
None
None
 1.18A 1sh9A-2b1nA:
undetectable		 1sh9A-2b1nA:
17.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1STF_E_CCSE25_0
(PAPAIN
STEFIN B (CYSTATIN
B))		 2b1n SPE31
(Pachyrhizus
erosus) 		7 / 10 GLN A  20
GLY A  24
SER A  25
TRP A  27
PHE A  29
SER A  30
HIS A 168
 None
 0.52A 1stfE-2b1nA:
33.5
1stfI-2b1nA:
undetectable		 1stfE-2b1nA:
41.56
1stfI-2b1nA:
17.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AI8_A_HNQA255_1
(CATHEPSIN B)		 2b1n SPE31
(Pachyrhizus
erosus) 		4 / 7 GLN A  20
GLY A  24
HIS A 168
TRP A 190
 None
 0.61A 3ai8A-2b1nA:
26.4		 3ai8A-2b1nA:
30.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2b1n SPE31
(Pachyrhizus
erosus) 		4 / 8 SER A  72
VAL A  76
VAL A  58
TRP A  75
 None
 1.01A 3nlrA-2b1nA:
undetectable
3nlrB-2b1nA:
undetectable		 3nlrA-2b1nA:
19.29
3nlrB-2b1nA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 2b1n SPE31
(Pachyrhizus
erosus) 		4 / 5 PHE A 218
ILE A 115
GLY A 112
HIS A  69
 None
 1.34A 3r0lD-2b1nA:
undetectable		 3r0lD-2b1nA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2b1n SPE31
(Pachyrhizus
erosus) 		5 / 9 ASP A  94
ILE A  55
GLY A  63
GLN A  20
GLY A  26
 None
 1.38A 4acaB-2b1nA:
undetectable
4acaC-2b1nA:
undetectable		 4acaB-2b1nA:
18.05
4acaC-2b1nA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_C_OBNC2004_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2b1n SPE31
(Pachyrhizus
erosus) 		5 / 12 LEU A  46
ALA A  37
PHE A  29
THR A  15
ILE A  14
 None
 1.19A 4hytC-2b1nA:
undetectable		 4hytC-2b1nA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 2b1n SPE31
(Pachyrhizus
erosus) 		4 / 5 GLY A  26
SER A  25
ALA A  28
GLU A  51
 None
 0.94A 4m93B-2b1nA:
undetectable
4m93C-2b1nA:
undetectable		 4m93B-2b1nA:
19.77
4m93C-2b1nA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_1
(UNCHARACTERIZED
PROTEIN MJ0489)		 2b1n SPE31
(Pachyrhizus
erosus) 		4 / 4 LYS A  18
ASP A  56
GLU A  85
THR A  32
 None
 1.39A 5d4uA-2b1nA:
0.1		 5d4uA-2b1nA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_1
(UNCHARACTERIZED
PROTEIN MJ0489)		 2b1n SPE31
(Pachyrhizus
erosus) 		4 / 4 LYS A  18
ASP A  56
GLU A  85
THR A  32
 None
 1.41A 5d4uB-2b1nA:
0.0		 5d4uB-2b1nA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_1
(UNCHARACTERIZED
PROTEIN MJ0489)		 2b1n SPE31
(Pachyrhizus
erosus) 		4 / 4 LYS A  18
ASP A  56
GLU A  85
THR A  32
 None
 1.39A 5d4uC-2b1nA:
0.0		 5d4uC-2b1nA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN MJ0489)		 2b1n SPE31
(Pachyrhizus
erosus) 		4 / 4 LYS A  18
ASP A  56
GLU A  85
THR A  32
 None
 1.39A 5d4uD-2b1nA:
0.0		 5d4uD-2b1nA:
19.94