SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2b1u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2b1u CALMODULIN-LIKE
PROTEIN 5
(Homo
sapiens) 		6 / 12 LEU A 103
MET A 107
LEU A 110
MET A 122
GLU A 125
VAL A 134
 None
 1.19A 1lxfC-2b1uA:
3.8		 1lxfC-2b1uA:
35.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CJK_C_ACTC301_0
(IMMUNOGLOBULIN FAB
LIGHT CHAIN)		 2b1u CALMODULIN-LIKE
PROTEIN 5
(Homo
sapiens) 		4 / 4 VAL A 100
GLY A 132
ASP A 131
ASP A 127
 None
 1.26A 6cjkC-2b1uA:
undetectable		 6cjkC-2b1uA:
10.90