SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2b2y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K7A_A_MXDA1002_1 (ANDROGEN RECEPTOR)	2b2y	CHROMODOMAIN-HELICAS E-DNA-BINDING PROTEIN 1 (Homo sapiens)	3 / 3	GLU C 14 TRP C 64 LYS C 11	None	1.50A	4k7aA-2b2yC: undetectable	4k7aA-2b2yC: 15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X3U_B_SVRB101_1 (CHROMOBOX PROTEIN HOMOLOG 7)	2b2y	CHROMODOMAIN-HELICAS E-DNA-BINDING PROTEIN 1 (Homo sapiens)	5 / 9	ARG C 23 LEU C 61 TRP C 64 THR C 73 TRP C 74	None	0.28A	4x3uA-2b2yC: 5.4	4x3uA-2b2yC: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X3U_B_SVRB101_2 (CHROMOBOX PROTEIN HOMOLOG 7)	2b2y	CHROMODOMAIN-HELICAS E-DNA-BINDING PROTEIN 1 (Homo sapiens)	5 / 10	ARG C 23 LEU C 61 TRP C 64 THR C 73 TRP C 74	None	0.29A	4x3uB-2b2yC: 5.4	4x3uB-2b2yC: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KIR_A_RCXA601_2 (PROSTAGLANDIN G/H SYNTHASE 2)	2b2y	CHROMODOMAIN-HELICAS E-DNA-BINDING PROTEIN 1 (Homo sapiens)	3 / 3	ARG C 18 ILE C 62 PHE C 19	None	0.76A	5kirA-2b2yC: undetectable	5kirA-2b2yC: 11.65

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4K7A_A_MXDA1002_1","ANDROGEN RECEPTOR","2b2y","CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1","Homo sapiens",3,"GLU C  14;TRP C  64;LYS C  11","None","1.50A","4k7aA-2b2yC:undetectable","4k7aA-2b2yC:15.26"],["4X3U_B_SVRB101_1","CHROMOBOX PROTEIN HOMOLOG 7;CHROMOBOX PROTEIN HOMOLOG 7","2b2y","CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1","Homo sapiens",5,"ARG C  23;LEU C  61;TRP C  64;THR C  73;TRP C  74","None","0.28A","4x3uA-2b2yC:5.4","4x3uA-2b2yC:25.00"],["4X3U_B_SVRB101_2","CHROMOBOX PROTEIN HOMOLOG 7","2b2y","CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1","Homo sapiens",5,"ARG C  23;LEU C  61;TRP C  64;THR C  73;TRP C  74","None","0.29A","4x3uB-2b2yC:5.4","4x3uB-2b2yC:25.00"],["5KIR_A_RCXA601_2","PROSTAGLANDIN G\/H SYNTHASE 2","2b2y","CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1","Homo sapiens",3,"ARG C  18;ILE C  62;PHE C  19","None","0.76A","5kirA-2b2yC:undetectable","5kirA-2b2yC:11.65"]]