SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2b3r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T86_A_CAMA1422_0 (CYTOCHROME P450-CAM)	2b3r	PHOSPHATIDYLINOSITOL -4-PHOSPHATE 3-KINASE C2 DOMAIN-CONTAINING ALPHA POLYPEPTIDE (Mus musculus)	4 / 8	THR A1441 THR A1435 VAL A1469 VAL A1419	None	0.84A	1t86A-2b3rA: undetectable	1t86A-2b3rA: 17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZB7_A_NCAA901_0 (PROSTAGLANDIN REDUCTASE 2)	2b3r	PHOSPHATIDYLINOSITOL -4-PHOSPHATE 3-KINASE C2 DOMAIN-CONTAINING ALPHA POLYPEPTIDE (Mus musculus)	4 / 5	TYR A1452 ILE A1399 LEU A1493 LEU A1488	None None SO4 A 303 (-4.0A) None	1.11A	2zb7A-2b3rA: undetectable	2zb7A-2b3rA: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UC3_A_486A801_2 (GLUCOCORTICOID RECEPTOR)	2b3r	PHOSPHATIDYLINOSITOL -4-PHOSPHATE 3-KINASE C2 DOMAIN-CONTAINING ALPHA POLYPEPTIDE (Mus musculus)	4 / 5	LEU A1465 LEU A1467 MET A1449 TYR A1392	None	1.44A	5uc3A-2b3rA: undetectable	5uc3A-2b3rA: 23.62