SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2b3w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 2b3w HYPOTHETICAL PROTEIN
YBIA
(Escherichia
coli) 		5 / 12 LEU A 145
LEU A 149
PHE A  19
GLU A 125
SER A  47
 None
 0.99A 4aqlA-2b3wA:
undetectable		 4aqlA-2b3wA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 2b3w HYPOTHETICAL PROTEIN
YBIA
(Escherichia
coli) 		3 / 3 PHE A  19
THR A  46
LEU A 145
 None
 0.52A 4qztA-2b3wA:
undetectable		 4qztA-2b3wA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 2b3w HYPOTHETICAL PROTEIN
YBIA
(Escherichia
coli) 		5 / 11 TYR A  20
SER A  30
THR A  22
ALA A  74
ASP A 130
 None
 1.40A 4zjoD-2b3wA:
1.8		 4zjoD-2b3wA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 2b3w HYPOTHETICAL PROTEIN
YBIA
(Escherichia
coli) 		5 / 11 TYR A  20
SER A  30
THR A  22
ALA A  74
THR A 127
 None
 1.41A 4zjoD-2b3wA:
1.8		 4zjoD-2b3wA:
10.87