SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2b44'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 2b44 GLYCYL-GLYCINE
ENDOPEPTIDASE LYTM
(Staphylococcus
aureus) 		4 / 8 HIS A 293
GLY A 240
GLY A 285
ASP A 214
 ZN  A 400 ( 3.1A)
None
PO4  A 500 (-3.6A)
ZN  A 400 ( 2.2A)
 0.77A 1aegA-2b44A:
undetectable		 1aegA-2b44A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_B_9TPB601_1
(SERUM ALBUMIN)		 2b44 GLYCYL-GLYCINE
ENDOPEPTIDASE LYTM
(Staphylococcus
aureus) 		5 / 12 TYR A 258
ILE A 278
LEU A 192
LEU A 226
GLY A 275
 None
 1.19A 4l9qB-2b44A:
undetectable		 4l9qB-2b44A:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 2b44 GLYCYL-GLYCINE
ENDOPEPTIDASE LYTM
(Staphylococcus
aureus) 		3 / 3 MET A 217
MET A 259
TYR A 224
 None
 1.27A 4p6xI-2b44A:
undetectable		 4p6xI-2b44A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QCK_A_ASDA404_1
(3-KETOSTEROID-9-ALPH
A-MONOOXYGENASE
OXYGENASE SUBUNIT)		 2b44 GLYCYL-GLYCINE
ENDOPEPTIDASE LYTM
(Staphylococcus
aureus) 		5 / 12 HIS A 291
ALA A 279
ASN A 261
ASN A 262
GLY A 285
 PO4  A 500 (-3.9A)
None
None
None
PO4  A 500 (-3.6A)
 1.29A 4qckA-2b44A:
undetectable		 4qckA-2b44A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)		 2b44 GLYCYL-GLYCINE
ENDOPEPTIDASE LYTM
(Staphylococcus
aureus) 		3 / 3 TYR A 215
ALA A 189
LEU A 313
 None
 0.66A 6d9kF-2b44A:
undetectable		 6d9kF-2b44A:
10.03