SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2b4q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_1
(PROTEIN (PROTEASE))		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 ARG A  85
GLY A 237
ALA A 236
VAL A  90
ILE A  25
 None
 1.03A 1c6zA-2b4qA:
undetectable		 1c6zA-2b4qA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_2
(PROTEIN (PROTEASE))		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 ARG A  85
GLY A 237
ALA A 236
VAL A  90
ILE A  25
 None
 0.95A 1c6zB-2b4qA:
undetectable		 1c6zB-2b4qA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_1
(PROTEIN (HIV-1
PROTEASE))		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 10 LEU A  79
ALA A  64
ASP A  65
GLY A  16
PHE A  37
 None
None
NAP  A1901 (-3.8A)
NAP  A1901 (-3.2A)
None
 1.19A 1d4sA-2b4qA:
undetectable		 1d4sA-2b4qA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_1
(HIV-1 PROTEASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 9 GLY A 237
VAL A  90
ILE A  25
GLY A  28
ILE A  88
 None
 0.93A 1hpvA-2b4qA:
undetectable		 1hpvA-2b4qA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_2
(PROTEASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 237
ALA A 236
ILE A  25
GLY A  28
ILE A  88
 None
 0.82A 1muiB-2b4qA:
undetectable		 1muiB-2b4qA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		6 / 12 TYR A 162
ILE A  21
GLY A 147
ALA A 167
SER A 165
GLY A 193
 NAP  A1901 (-4.5A)
NAP  A1901 (-3.9A)
None
None
None
NAP  A1901 (-4.7A)
 1.28A 1nbiA-2b4qA:
7.3		 1nbiA-2b4qA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		6 / 12 TYR A 162
ILE A  21
GLY A 147
ALA A 167
SER A 165
GLY A 193
 NAP  A1901 (-4.5A)
NAP  A1901 (-3.9A)
None
None
None
NAP  A1901 (-4.7A)
 1.27A 1nbiB-2b4qA:
7.3		 1nbiB-2b4qA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 TYR A 162
GLY A 147
ALA A 167
SER A 165
GLY A 193
 NAP  A1901 (-4.5A)
None
None
None
NAP  A1901 (-4.7A)
 1.28A 1nbiC-2b4qA:
7.2		 1nbiC-2b4qA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 TYR A 162
GLY A 147
ALA A 167
SER A 165
GLY A 193
 NAP  A1901 (-4.5A)
None
None
None
NAP  A1901 (-4.7A)
 1.27A 1nbiD-2b4qA:
7.3		 1nbiD-2b4qA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_3
(POL POLYPROTEIN)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		6 / 12 GLY A 237
ALA A 236
VAL A  90
ILE A  25
GLY A  28
ILE A  88
 None
 1.06A 2avvB-2b4qA:
undetectable		 2avvB-2b4qA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  16
ARG A  41
ASP A  65
SER A  67
ALA A  93
 NAP  A1901 (-3.2A)
NAP  A1901 (-3.6A)
NAP  A1901 (-3.8A)
NAP  A1901 (-4.0A)
NAP  A1901 (-3.8A)
 0.87A 2br4C-2b4qA:
4.9		 2br4C-2b4qA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		6 / 12 ARG A  85
GLY A 237
ALA A 236
VAL A  90
ILE A  25
ILE A  88
 None
 1.19A 2o4kB-2b4qA:
undetectable		 2o4kB-2b4qA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		6 / 12 ARG A  85
GLY A 237
ALA A 236
VAL A  90
ILE A  25
ILE A  88
 None
 1.16A 2o4lB-2b4qA:
undetectable		 2o4lB-2b4qA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 7 ASN A  92
GLY A  94
THR A  95
SER A 197
 NAP  A1901 (-3.0A)
NAP  A1901 (-3.0A)
None
NAP  A1901 (-3.4A)
 1.21A 2o5yH-2b4qA:
undetectable
2o5yL-2b4qA:
undetectable		 2o5yH-2b4qA:
19.93
2o5yL-2b4qA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		6 / 12 GLY A 237
ALA A 236
VAL A  90
ILE A  25
GLY A  28
ILE A  88
 None
 1.07A 3bvbA-2b4qA:
undetectable		 3bvbA-2b4qA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 ARG A  85
GLY A 237
ALA A 236
GLY A  28
ILE A  88
 None
 0.96A 3cyxB-2b4qA:
undetectable		 3cyxB-2b4qA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_2
(PROTEASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 236
VAL A  90
ILE A  25
GLY A  28
ILE A  88
 None
 0.98A 3em3B-2b4qA:
undetectable		 3em3B-2b4qA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 115
PHE A 121
GLN A 125
ILE A 185
LEU A 169
 NAP  A1901 (-4.7A)
None
None
None
None
 1.12A 3gwxB-2b4qA:
undetectable		 3gwxB-2b4qA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		6 / 12 GLY A 237
ALA A 236
VAL A  90
ILE A  25
GLY A  28
ILE A  88
 None
 1.04A 3jw2B-2b4qA:
undetectable		 3jw2B-2b4qA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		6 / 12 GLY A 237
ALA A 236
VAL A  90
ILE A  25
GLY A  28
ILE A  88
 None
 1.04A 3k4vB-2b4qA:
undetectable		 3k4vB-2b4qA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_2
(HIV-1 PROTEASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 236
VAL A  90
ILE A  25
GLY A  28
ILE A  88
 None
 1.05A 3oxvB-2b4qA:
undetectable		 3oxvB-2b4qA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_2
(HIV-1 PROTEASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 11 ALA A 236
VAL A  90
ILE A  25
GLY A  28
ILE A  88
 None
 0.96A 3oxvD-2b4qA:
undetectable		 3oxvD-2b4qA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_2
(HIV-1 PROTEASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 236
VAL A  90
ILE A  25
GLY A  28
ILE A  88
 None
 0.94A 3oxwB-2b4qA:
undetectable		 3oxwB-2b4qA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 ARG A  85
GLY A 237
ALA A 236
VAL A  90
ILE A  25
 None
 1.05A 3oxxA-2b4qA:
undetectable		 3oxxA-2b4qA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 ARG A  85
GLY A 237
ALA A 236
VAL A  90
ILE A  25
 None
 0.99A 3tkgD-2b4qA:
undetectable		 3tkgD-2b4qA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		6 / 12 ARG A  85
GLY A 237
ALA A 236
VAL A  90
ILE A  25
ILE A  88
 None
 1.09A 3tl9B-2b4qA:
undetectable		 3tl9B-2b4qA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		6 / 12 GLY A 237
ALA A 236
VAL A  90
ILE A  25
GLY A  28
ILE A  88
 None
 0.99A 3tl9B-2b4qA:
undetectable		 3tl9B-2b4qA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 162
VAL A 112
SER A  96
GLY A  94
 NAP  A1901 (-4.5A)
None
None
NAP  A1901 (-3.0A)
 1.28A 3v4tA-2b4qA:
undetectable
3v4tD-2b4qA:
undetectable		 3v4tA-2b4qA:
22.14
3v4tD-2b4qA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 7 ILE A 217
ARG A 194
GLY A 193
VAL A 149
 None
None
NAP  A1901 (-4.7A)
None
 0.97A 4a3uB-2b4qA:
undetectable		 4a3uB-2b4qA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		6 / 12 GLY A 237
ALA A 236
VAL A  90
ILE A  25
GLY A  28
ILE A  88
 None
 1.07A 4jecA-2b4qA:
undetectable		 4jecA-2b4qA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A 163
ALA A 168
LEU A 169
GLY A 147
ALA A  76
 None
 1.22A 4l6v1-2b4qA:
undetectable
4l6v6-2b4qA:
undetectable		 4l6v1-2b4qA:
17.47
4l6v6-2b4qA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_1
(PROTEASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 11 ALA A 236
VAL A  90
ILE A  25
GLY A  28
ILE A  88
 None
 0.88A 4njtC-2b4qA:
undetectable		 4njtC-2b4qA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_1
(PROTEASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A 237
VAL A  90
ILE A  25
GLY A  28
ILE A  88
 None
 0.99A 4njvC-2b4qA:
undetectable		 4njvC-2b4qA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 159
SER A  96
GLY A 156
ALA A 150
SER A 148
 None
None
None
None
NAP  A1901 (-3.1A)
 1.31A 5l66K-2b4qA:
undetectable
5l66L-2b4qA:
undetectable		 5l66K-2b4qA:
20.57
5l66L-2b4qA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 159
SER A  96
GLY A 156
ALA A 150
SER A 148
 None
None
None
None
NAP  A1901 (-3.1A)
 1.32A 5l66Y-2b4qA:
undetectable
5l66Z-2b4qA:
undetectable		 5l66Y-2b4qA:
20.57
5l66Z-2b4qA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_1_PQN1842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 10 ALA A  34
LEU A  29
GLY A  28
ILE A 124
LEU A 176
 None
 1.21A 5oy01-2b4qA:
undetectable
5oy07-2b4qA:
undetectable		 5oy01-2b4qA:
13.08
5oy07-2b4qA:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YK2_A_ERYA501_0
(PROBABLE CONSERVED
ATP-BINDING PROTEIN
ABC TRANSPORTER)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A 194
GLY A 147
ALA A 191
PRO A 249
ILE A 152
 None
 1.08A 5yk2A-2b4qA:
undetectable		 5yk2A-2b4qA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 237
ALA A 236
VAL A  90
ILE A  25
ILE A  88
 None
 0.95A 6dh6A-2b4qA:
undetectable		 6dh6A-2b4qA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		6 / 12 ARG A  85
GLY A 237
ALA A 236
VAL A  90
ILE A  25
ILE A  88
 None
 1.23A 6dilB-2b4qA:
undetectable		 6dilB-2b4qA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)		 2b4q RHAMNOLIPIDS
BIOSYNTHESIS
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 236
VAL A  90
ILE A  25
GLY A  28
ILE A  88
 None
 0.96A 6dj2A-2b4qA:
undetectable		 6dj2A-2b4qA:
16.13