SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2b5l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P9G_A_ACTA42_0
(EAFP 2)		 2b5l NONSTRUCTURAL
PROTEIN V
(Mammalian
rubulavirus
5) 		3 / 3 CYH C 190
ARG C 173
CYH C 215
 ZN  C3002 (-2.2A)
None
ZN  C3002 (-2.2A)
 1.43A 1p9gA-2b5lC:
undetectable		 1p9gA-2b5lC:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX3_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 2b5l NONSTRUCTURAL
PROTEIN V
(Mammalian
rubulavirus
5) 		3 / 3 LYS C 131
ILE C 177
THR C 111
 None
 0.87A 1rx3A-2b5lC:
undetectable		 1rx3A-2b5lC:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 2b5l NONSTRUCTURAL
PROTEIN V
(Mammalian
rubulavirus
5) 		3 / 3 CYH C 215
CYH C 190
HIS C 171
 ZN  C3002 (-2.2A)
ZN  C3002 (-2.2A)
ZN  C3002 (-4.0A)
 0.76A 2iwkA-2b5lC:
undetectable		 2iwkA-2b5lC:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 2b5l NONSTRUCTURAL
PROTEIN V
(Mammalian
rubulavirus
5) 		3 / 3 CYH C 215
CYH C 190
HIS C 171
 ZN  C3002 (-2.2A)
ZN  C3002 (-2.2A)
ZN  C3002 (-4.0A)
 0.76A 2iwkB-2b5lC:
undetectable		 2iwkB-2b5lC:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 2b5l NONSTRUCTURAL
PROTEIN V
(Mammalian
rubulavirus
5) 		3 / 3 CYH C 215
CYH C 190
HIS C 171
 ZN  C3002 (-2.2A)
ZN  C3002 (-2.2A)
ZN  C3002 (-4.0A)
 0.61A 3dtuB-2b5lC:
undetectable		 3dtuB-2b5lC:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 2b5l NONSTRUCTURAL
PROTEIN V
(Mammalian
rubulavirus
5) 		3 / 3 CYH C 215
CYH C 190
HIS C 171
 ZN  C3002 (-2.2A)
ZN  C3002 (-2.2A)
ZN  C3002 (-4.0A)
 0.59A 3dtuD-2b5lC:
undetectable		 3dtuD-2b5lC:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 2b5l NONSTRUCTURAL
PROTEIN V
(Mammalian
rubulavirus
5) 		4 / 6 SER C  37
GLN C  30
GLU C  25
THR C  19
 None
 1.48A 6djzA-2b5lC:
undetectable		 6djzA-2b5lC:
19.76