SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2b5m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FFY_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 12 ASN A 211
GLY A 187
ASP A 184
GLN A 186
VAL A 181
 None
 1.12A 1ffyA-2b5mA:
undetectable		 1ffyA-2b5mA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_2
(HIV-II PROTEASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 8 ASP A 275
GLY A 233
ILE A 232
PRO A 250
ILE A 252
 None
 1.24A 1hshD-2b5mA:
undetectable		 1hshD-2b5mA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A 270
VAL A 324
VAL A 322
LEU A 272
 None
 0.86A 1igxA-2b5mA:
undetectable		 1igxA-2b5mA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHV_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 8 GLY A 242
GLY A 172
LEU A 170
GLY A 227
 None
 0.77A 1jhvA-2b5mA:
undetectable		 1jhvA-2b5mA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWE_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 7 LEU A  31
VAL A  15
GLY A  17
TYR A  42
 None
 0.95A 1lweA-2b5mA:
undetectable		 1lweA-2b5mA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		3 / 3 ASP A 403
THR A 698
GLU A 398
 None
 0.81A 1pj7A-2b5mA:
undetectable		 1pj7A-2b5mA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 12 LEU A 273
LEU A 284
LEU A 300
ILE A 220
GLY A 268
 None
 1.01A 1qknA-2b5mA:
undetectable		 1qknA-2b5mA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 7 SER A 661
ILE A 394
ILE A 707
THR A 646
 None
 1.00A 1sbrB-2b5mA:
undetectable		 1sbrB-2b5mA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		3 / 3 ILE A  88
ASP A  75
PHE A  23
 None
 0.41A 1uwjB-2b5mA:
undetectable		 1uwjB-2b5mA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 8 VAL A 222
THR A 238
TYR A 271
LEU A 285
 None
 0.93A 1z2bB-2b5mA:
undetectable		 1z2bB-2b5mA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B9E_A_SAMA1201_0
(NOL1/NOP2/SUN DOMAIN
FAMILY, MEMBER 5
ISOFORM 2)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 12 PRO A 545
GLY A 551
LEU A 541
ASP A 542
PHE A 574
 None
 1.45A 2b9eA-2b5mA:
undetectable		 2b9eA-2b5mA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPM_A_SAMA300_0
(PROTEIN
(ADENINE-SPECIFIC
METHYLTRANSFERASE
DPNII 1))		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 12 PHE A 975
GLY A1087
ALA A1085
PHE A 965
ASN A 964
 None
 1.13A 2dpmA-2b5mA:
undetectable		 2dpmA-2b5mA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 5 PRO A 681
PHE A 650
PHE A 641
ILE A 396
 None
 1.10A 2hjhA-2b5mA:
undetectable		 2hjhA-2b5mA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 12 VAL A 866
ILE A 830
TYR A 891
LEU A 736
ALA A 882
 None
 1.30A 2iyfB-2b5mA:
undetectable		 2iyfB-2b5mA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 12 ILE A1068
VAL A 108
LEU A  80
PHE A  78
ALA A 104
 None
 1.25A 2jj8C-2b5mA:
undetectable		 2jj8C-2b5mA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		3 / 3 GLY A 329
ASP A 330
SER A 309
 None
 0.52A 2qhfA-2b5mA:
undetectable		 2qhfA-2b5mA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 11 LEU A 699
LEU A 673
VAL A 676
LEU A 425
ILE A 704
 None
 1.22A 2uxoB-2b5mA:
0.0		 2uxoB-2b5mA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 8 ILE A 258
GLY A 274
LEU A 280
LEU A 305
 None
 0.78A 2vctA-2b5mA:
undetectable		 2vctA-2b5mA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 8 ILE A 258
GLY A 274
LEU A 280
LEU A 305
 None
 0.74A 2vctB-2b5mA:
undetectable		 2vctB-2b5mA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_A_RBFA200_1
(DODECIN)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A 369
ARG A 391
GLN A 372
HIS A 797
 None
 1.07A 2vxaA-2b5mA:
undetectable
2vxaC-2b5mA:
undetectable
2vxaE-2b5mA:
undetectable		 2vxaA-2b5mA:
5.69
2vxaC-2b5mA:
5.69
2vxaE-2b5mA:
5.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_B_RBFB200_1
(DODECIN)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A 391
GLN A 372
ARG A 369
HIS A 797
 None
 1.04A 2vxaA-2b5mA:
undetectable
2vxaB-2b5mA:
undetectable
2vxaK-2b5mA:
undetectable		 2vxaA-2b5mA:
5.69
2vxaB-2b5mA:
5.69
2vxaK-2b5mA:
5.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_C_RBFC200_1
(DODECIN)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A 391
GLN A 372
ARG A 369
HIS A 797
 None
 1.06A 2vxaB-2b5mA:
undetectable
2vxaC-2b5mA:
undetectable
2vxaG-2b5mA:
undetectable		 2vxaB-2b5mA:
5.69
2vxaC-2b5mA:
5.69
2vxaG-2b5mA:
5.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_D_RBFD200_1
(DODECIN)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A 369
ARG A 391
GLN A 372
HIS A 797
 None
 1.07A 2vxaD-2b5mA:
undetectable
2vxaF-2b5mA:
undetectable
2vxaI-2b5mA:
undetectable		 2vxaD-2b5mA:
5.69
2vxaF-2b5mA:
5.69
2vxaI-2b5mA:
5.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_E_RBFE200_1
(DODECIN)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A 391
GLN A 372
ARG A 369
HIS A 797
 None
 1.05A 2vxaD-2b5mA:
undetectable
2vxaE-2b5mA:
undetectable
2vxaL-2b5mA:
undetectable		 2vxaD-2b5mA:
5.69
2vxaE-2b5mA:
5.69
2vxaL-2b5mA:
5.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_H_RBFH200_1
(DODECIN)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 8 HIS A 797
ARG A 391
GLN A 372
ARG A 369
 None
 1.08A 2vxaB-2b5mA:
undetectable
2vxaG-2b5mA:
undetectable
2vxaH-2b5mA:
undetectable		 2vxaB-2b5mA:
5.69
2vxaG-2b5mA:
5.69
2vxaH-2b5mA:
5.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_I_RBFI200_1
(DODECIN)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A 391
GLN A 372
ARG A 369
HIS A 797
 None
 1.05A 2vxaH-2b5mA:
undetectable
2vxaI-2b5mA:
undetectable
2vxaJ-2b5mA:
undetectable		 2vxaH-2b5mA:
5.69
2vxaI-2b5mA:
5.69
2vxaJ-2b5mA:
5.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_J_RBFJ200_1
(DODECIN)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 8 HIS A 797
ARG A 369
ARG A 391
GLN A 372
 None
 1.07A 2vxaD-2b5mA:
undetectable
2vxaJ-2b5mA:
undetectable
2vxaL-2b5mA:
undetectable		 2vxaD-2b5mA:
5.69
2vxaJ-2b5mA:
5.69
2vxaL-2b5mA:
5.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_K_RBFK200_1
(DODECIN)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 8 HIS A 797
ARG A 391
GLN A 372
ARG A 369
 None
 1.05A 2vxaH-2b5mA:
undetectable
2vxaJ-2b5mA:
undetectable
2vxaK-2b5mA:
undetectable		 2vxaH-2b5mA:
5.69
2vxaJ-2b5mA:
5.69
2vxaK-2b5mA:
5.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_L_RBFL200_1
(DODECIN)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 8 HIS A 797
ARG A 391
GLN A 372
ARG A 369
 None
 1.06A 2vxaA-2b5mA:
undetectable
2vxaK-2b5mA:
undetectable
2vxaL-2b5mA:
undetectable		 2vxaA-2b5mA:
5.69
2vxaK-2b5mA:
5.69
2vxaL-2b5mA:
5.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 8 LEU A1051
ILE A1094
LEU A1136
THR A1024
LEU A1043
 None
 1.24A 2xfhA-2b5mA:
undetectable		 2xfhA-2b5mA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKK_E_MFXE1100_1
(TOPOISOMERASE IV
DNA)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		3 / 3 ARG A 327
GLU A 787
SER A 326
 None
 0.75A 2xkkA-2b5mA:
undetectable
2xkkC-2b5mA:
undetectable		 2xkkA-2b5mA:
22.20
2xkkC-2b5mA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 6 ASP A1099
ILE A1100
LEU A1058
TYR A  58
 None
 1.04A 2ya7A-2b5mA:
12.0		 2ya7A-2b5mA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 6 ASP A1099
ILE A1100
LEU A1058
TYR A  58
 None
 1.04A 2ya7B-2b5mA:
10.9		 2ya7B-2b5mA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 6 ASP A1099
ILE A1100
LEU A1058
TYR A  58
 None
 1.04A 2ya7D-2b5mA:
8.3		 2ya7D-2b5mA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		3 / 3 MET A 938
GLU A 943
ASP A 986
 None
 1.04A 3a25A-2b5mA:
undetectable		 3a25A-2b5mA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_E_VD3E2001_1
(VITAMIN D
HYDROXYLASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 12 PRO A  12
THR A  13
ILE A 359
ILE A 390
LEU A1029
 None
 1.22A 3a50E-2b5mA:
undetectable		 3a50E-2b5mA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 7 ILE A1037
GLN A  10
GLY A1038
LEU A1000
 None
 0.59A 3bjwB-2b5mA:
undetectable		 3bjwB-2b5mA:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 7 ILE A1037
GLN A  10
GLY A1038
LEU A1000
 None
 0.62A 3bjwF-2b5mA:
undetectable		 3bjwF-2b5mA:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 7 ILE A1037
GLN A  10
GLY A1038
LEU A1000
 None
 0.57A 3bjwH-2b5mA:
undetectable		 3bjwH-2b5mA:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_4
(HIV-1 PROTEASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 4 LEU A  32
ASP A 318
VAL A  43
THR A  24
 None
 1.31A 3cyxB-2b5mA:
undetectable		 3cyxB-2b5mA:
6.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 8 LEU A1000
ASN A1005
THR A 377
VAL A1004
GLY A1038
 None
 1.33A 3dcjB-2b5mA:
undetectable		 3dcjB-2b5mA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		3 / 3 TYR A 171
TYR A 271
ILE A 220
 None
 0.85A 3eteA-2b5mA:
undetectable
3eteB-2b5mA:
undetectable		 3eteA-2b5mA:
19.20
3eteB-2b5mA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 7 GLU A 958
VAL A1040
VAL A1004
ALA A 968
 None
 0.77A 3kp6B-2b5mA:
undetectable		 3kp6B-2b5mA:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_1
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 10 VAL A1006
VAL A1004
LEU A1000
GLY A1031
GLY A1038
 None
 1.32A 3ls4H-2b5mA:
undetectable		 3ls4H-2b5mA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 8 SER A 730
SER A 818
LEU A 821
ASP A 824
 None
 1.05A 3m0wE-2b5mA:
undetectable
3m0wF-2b5mA:
undetectable
3m0wG-2b5mA:
undetectable
3m0wH-2b5mA:
undetectable		 3m0wE-2b5mA:
7.20
3m0wF-2b5mA:
7.20
3m0wG-2b5mA:
7.20
3m0wH-2b5mA:
7.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 7 GLU A 489
ARG A 477
THR A 472
ALA A 474
 None
 1.21A 3mbgA-2b5mA:
undetectable
3mbgB-2b5mA:
undetectable		 3mbgA-2b5mA:
8.61
3mbgB-2b5mA:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 12 VAL A 324
VAL A  15
GLY A 325
LEU A 333
GLU A  40
 None
 1.24A 3medA-2b5mA:
undetectable
3medB-2b5mA:
undetectable		 3medA-2b5mA:
19.11
3medB-2b5mA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_1
(ENDOTHIAPEPSIN)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 10 ALA A 154
TYR A  84
LEU A 135
ILE A  79
ILE A1068
 None
 1.11A 3prsA-2b5mA:
undetectable		 3prsA-2b5mA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB1_0
(INVASIN IPAD)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 7 ILE A 359
LEU A 356
LEU A 710
VAL A1013
 None
 0.81A 3r9vA-2b5mA:
undetectable
3r9vB-2b5mA:
undetectable		 3r9vA-2b5mA:
15.08
3r9vB-2b5mA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		3 / 3 ASN A1034
ALA A  14
LYS A  35
 None
 1.01A 3runA-2b5mA:
undetectable		 3runA-2b5mA:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_2
(PROTEASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 9 ASP A 275
GLY A 233
ILE A 232
PRO A 250
ILE A 252
 None
 1.11A 3s56B-2b5mA:
undetectable		 3s56B-2b5mA:
6.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA1001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 5 LEU A 582
GLY A 583
PHE A 612
ARG A 626
 None
 0.99A 3smtA-2b5mA:
undetectable		 3smtA-2b5mA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 6 THR A 657
ASN A 670
GLY A 393
ILE A 707
 None
 0.97A 3w9tF-2b5mA:
undetectable		 3w9tF-2b5mA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 5 HIS A 522
GLN A 520
SER A 506
VAL A 463
 None
 1.38A 4a99D-2b5mA:
undetectable		 4a99D-2b5mA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 5 ILE A1130
LYS A1131
GLU A1134
PHE A 612
 None
 1.40A 4acbC-2b5mA:
undetectable		 4acbC-2b5mA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 10 VAL A 322
LEU A 336
VAL A 334
LEU A 280
VAL A 347
 None
 1.03A 4e3hA-2b5mA:
undetectable		 4e3hA-2b5mA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		6 / 10 LEU A 673
ILE A 396
GLY A 395
GLY A 393
SER A 653
THR A 657
 None
 1.14A 4fakA-2b5mA:
undetectable		 4fakA-2b5mA:
8.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 7 GLY A 227
GLY A 228
TYR A 239
GLU A 224
 None
 0.86A 4fgkB-2b5mA:
undetectable		 4fgkB-2b5mA:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 8 LEU A 736
SER A 766
VAL A 866
GLY A 846
 None
 0.99A 4klrB-2b5mA:
undetectable		 4klrB-2b5mA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		3 / 3 ILE A1100
MET A1054
ARG A1057
 None
 0.82A 4lnwA-2b5mA:
undetectable		 4lnwA-2b5mA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_2
(THYROID HORMONE
RECEPTOR ALPHA)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		3 / 3 ILE A1100
MET A1054
ARG A1057
 None
 0.81A 4lnxA-2b5mA:
undetectable		 4lnxA-2b5mA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 11 VAL A 866
ILE A 830
TYR A 891
LEU A 736
ALA A 882
 None
 1.28A 4m83A-2b5mA:
undetectable		 4m83A-2b5mA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 12 CYH A  87
GLY A 106
ASN A 107
ILE A  79
GLY A1066
 None
 1.23A 4n48A-2b5mA:
undetectable		 4n48A-2b5mA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 6 THR A 860
LEU A 816
LEU A 880
GLU A 875
 None
 0.97A 4nc3A-2b5mA:
undetectable		 4nc3A-2b5mA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 6 GLU A1069
THR A1082
HIS A1077
ASN A 107
 None
 1.33A 4pfjB-2b5mA:
undetectable		 4pfjB-2b5mA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_B_SAMB401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 12 SER A 768
GLY A 832
LEU A 816
MET A 873
ILE A 848
 None
 1.19A 4pghB-2b5mA:
undetectable		 4pghB-2b5mA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_C_SAMC401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 11 SER A 768
GLY A 832
LEU A 816
MET A 873
ILE A 848
 None
 1.23A 4pghC-2b5mA:
undetectable		 4pghC-2b5mA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		3 / 3 GLU A 811
THR A 860
HIS A 805
 None
 0.83A 4q15A-2b5mA:
undetectable		 4q15A-2b5mA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		3 / 3 GLU A 811
THR A 860
HIS A 805
 None
 0.81A 4q15B-2b5mA:
undetectable		 4q15B-2b5mA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 11 GLY A 132
MET A 130
ILE A 178
GLY A 138
PHE A 155
 None
 1.09A 4qoiA-2b5mA:
undetectable
4qoiB-2b5mA:
undetectable		 4qoiA-2b5mA:
11.32
4qoiB-2b5mA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 11 MET A 130
ILE A 178
GLY A 138
ILE A 157
PHE A 155
 None
 0.97A 4qoiA-2b5mA:
undetectable
4qoiB-2b5mA:
undetectable		 4qoiA-2b5mA:
11.32
4qoiB-2b5mA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 8 THR A 308
GLU A 312
LEU A 272
GLY A 278
 None
 0.79A 4r3aA-2b5mA:
undetectable		 4r3aA-2b5mA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		3 / 3 GLU A 811
THR A 860
HIS A 805
 None
 0.83A 4ydqB-2b5mA:
undetectable		 4ydqB-2b5mA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESE_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 8 LEU A 710
ILE A 389
GLY A 373
LEU A1029
 None
 0.87A 5eseA-2b5mA:
undetectable		 5eseA-2b5mA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 12 VAL A 509
LEU A 602
LEU A 555
LEU A 546
THR A 594
 None
 1.13A 5hnwB-2b5mA:
undetectable		 5hnwB-2b5mA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		5 / 12 VAL A 509
LEU A 602
LEU A 555
LEU A 546
THR A 594
 None
 1.21A 5hnyB-2b5mA:
undetectable		 5hnyB-2b5mA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		3 / 3 SER A 766
SER A 768
PHE A 851
 None
 0.79A 5mugA-2b5mA:
undetectable		 5mugA-2b5mA:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A 270
TYR A 271
ASP A 275
GLY A 274
 None
 0.71A 5nooD-2b5mA:
undetectable		 5nooD-2b5mA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 7 THR A 860
LEU A 816
VAL A 870
GLU A 875
 None
 1.00A 5tudA-2b5mA:
undetectable		 5tudA-2b5mA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_2
(CYTOCHROME P450 3A4)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 7 ILE A 909
LEU A 881
PHE A 876
THR A 901
 None
 0.94A 5vc0A-2b5mA:
undetectable		 5vc0A-2b5mA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 6 PHE A1097
ASP A1090
LEU A1093
GLY A1091
 None
 0.96A 5x5qE-2b5mA:
undetectable		 5x5qE-2b5mA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		4 / 7 ALA A 566
ILE A 586
PHE A 612
LEU A 606
 None
 0.89A 6b5vA-2b5mA:
undetectable
6b5vB-2b5mA:
undetectable		 6b5vA-2b5mA:
5.73
6b5vB-2b5mA:
5.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_2
(GLUCOAMYLASE P)		 2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens) 		3 / 3 TRP A 893
GLU A 892
GLU A 896
 None
 0.95A 6fhwA-2b5mA:
undetectable		 6fhwA-2b5mA:
5.45