SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2b5y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 2b5y YKUV PROTEIN
(Bacillus
subtilis) 		4 / 7 PHE A  36
SER A  38
PHE A 106
ALA A 113
 None
 1.18A 1fxvA-2b5yA:
undetectable
1fxvB-2b5yA:
undetectable		 1fxvA-2b5yA:
20.00
1fxvB-2b5yA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 2b5y YKUV PROTEIN
(Bacillus
subtilis) 		3 / 3 MET A 133
ASN A  52
GLN A  92
 None
 0.89A 1xoqB-2b5yA:
undetectable		 1xoqB-2b5yA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 2b5y YKUV PROTEIN
(Bacillus
subtilis) 		4 / 7 HIS A  68
ILE A  90
ILE A  94
ALA A  66
 None
 0.83A 4lv9A-2b5yA:
undetectable		 4lv9A-2b5yA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_2
(CYP51 VARIANT1)		 2b5y YKUV PROTEIN
(Bacillus
subtilis) 		3 / 3 PRO A  70
LEU A  17
SER A  98
 None
 0.80A 5fsaB-2b5yA:
undetectable		 5fsaB-2b5yA:
14.08