SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2b61'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 7 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.21A 1v54A-2b61A:
undetectable
1v54C-2b61A:
undetectable		 1v54A-2b61A:
21.56
1v54C-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 7 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.22A 1v54N-2b61A:
undetectable
1v54P-2b61A:
undetectable		 1v54N-2b61A:
21.56
1v54P-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 6 GLU A 348
TYR A 344
ASP A  76
PHE A  82
 None
 1.31A 2a3bB-2b61A:
undetectable		 2a3bB-2b61A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 7 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.21A 2dyrA-2b61A:
undetectable
2dyrC-2b61A:
undetectable		 2dyrA-2b61A:
21.56
2dyrC-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 7 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.22A 2dyrN-2b61A:
undetectable
2dyrP-2b61A:
undetectable		 2dyrN-2b61A:
21.56
2dyrP-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 6 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.24A 2dysN-2b61A:
undetectable
2dysP-2b61A:
1.7		 2dysN-2b61A:
21.56
2dysP-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 7 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.23A 2eijN-2b61A:
undetectable
2eijP-2b61A:
undetectable		 2eijN-2b61A:
21.56
2eijP-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 7 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.22A 2eikN-2b61A:
undetectable
2eikP-2b61A:
undetectable		 2eikN-2b61A:
21.56
2eikP-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 7 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.20A 2eilN-2b61A:
undetectable
2eilP-2b61A:
undetectable		 2eilN-2b61A:
21.56
2eilP-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 6 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.18A 2eimN-2b61A:
undetectable
2eimP-2b61A:
1.7		 2eimN-2b61A:
21.56
2eimP-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 6 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.21A 2einA-2b61A:
undetectable
2einC-2b61A:
1.5		 2einA-2b61A:
21.56
2einC-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_A_CSCA1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 11 ARG A 212
TYR A 219
HIS A 337
ASP A 338
PHE A 340
 None
 0.80A 2vavA-2b61A:
43.4		 2vavA-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_A_CSCA1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 11 LEU A  49
THR A  50
ARG A 212
TYR A 219
HIS A 337
PHE A 340
 None
 0.62A 2vavA-2b61A:
43.4		 2vavA-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 ARG A 212
TYR A 219
HIS A 337
ASP A 338
PHE A 340
 None
 0.84A 2vavB-2b61A:
43.4		 2vavB-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
GLN A 253
 None
 0.99A 2vavB-2b61A:
43.4		 2vavB-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
HIS A 337
PHE A 340
 None
 0.63A 2vavB-2b61A:
43.4		 2vavB-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_C_CSCC1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
GLN A 253
 None
 0.91A 2vavC-2b61A:
43.5		 2vavC-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_C_CSCC1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
HIS A 337
PHE A 340
 None
 0.65A 2vavC-2b61A:
43.5		 2vavC-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_C_CSCC1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 LEU A  49
THR A  50
TYR A 219
TYR A 249
GLN A 253
 None
 0.99A 2vavC-2b61A:
43.5		 2vavC-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_C_CSCC1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 LEU A  49
THR A  50
TYR A 219
TYR A 249
HIS A 337
PHE A 340
 None
 0.79A 2vavC-2b61A:
43.5		 2vavC-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_D_CSCD1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
TYR A 249
GLN A 253
 None
 0.96A 2vavD-2b61A:
43.5		 2vavD-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_D_CSCD1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		7 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
TYR A 249
HIS A 337
PHE A 340
 None
 0.80A 2vavD-2b61A:
43.5		 2vavD-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_E_CSCE1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 ARG A 212
TYR A 219
HIS A 337
ASP A 338
PHE A 340
 None
 0.79A 2vavE-2b61A:
43.2		 2vavE-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_E_CSCE1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 THR A  50
ARG A 212
TYR A 219
HIS A 337
PHE A 340
 None
 0.64A 2vavE-2b61A:
43.2		 2vavE-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_E_CSCE1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 THR A  50
TYR A 219
TYR A 249
HIS A 337
PHE A 340
 None
 0.78A 2vavE-2b61A:
43.2		 2vavE-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_E_CSCE1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 TYR A 219
TYR A 249
HIS A 337
ASP A 338
PHE A 340
 None
 0.64A 2vavE-2b61A:
43.2		 2vavE-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 ARG A 212
TYR A 219
HIS A 337
ASP A 338
PHE A 340
 None
 0.86A 2vavG-2b61A:
43.3		 2vavG-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 THR A  50
ARG A 212
TYR A 219
HIS A 337
PHE A 340
 None
 0.75A 2vavG-2b61A:
43.3		 2vavG-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 THR A  50
TYR A 219
TYR A 249
HIS A 337
PHE A 340
 None
 0.83A 2vavG-2b61A:
43.3		 2vavG-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 TYR A 219
TYR A 249
HIS A 337
ASP A 338
PHE A 340
 None
 0.68A 2vavG-2b61A:
43.3		 2vavG-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
HIS A 337
 None
 0.61A 2vavH-2b61A:
43.3		 2vavH-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 LEU A  49
THR A  50
TYR A 219
TYR A 249
HIS A 337
 None
 0.75A 2vavH-2b61A:
43.3		 2vavH-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 TYR A 219
TYR A 249
PHE A 172
HIS A 337
ASP A 338
 None
 0.99A 2vavH-2b61A:
43.3		 2vavH-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_I_CSCI1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 ARG A 212
TYR A 219
HIS A 337
ASP A 338
PHE A 340
 None
 0.83A 2vavI-2b61A:
43.2		 2vavI-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_I_CSCI1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
GLN A 253
 None
 0.98A 2vavI-2b61A:
43.2		 2vavI-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_I_CSCI1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
HIS A 337
PHE A 340
 None
 0.62A 2vavI-2b61A:
43.2		 2vavI-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
GLN A 253
 None
 0.96A 2vavJ-2b61A:
43.2		 2vavJ-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
PHE A 340
 None
 0.72A 2vavJ-2b61A:
43.2		 2vavJ-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 LEU A  49
THR A  50
TYR A 219
TYR A 249
GLN A 253
 None
 1.02A 2vavJ-2b61A:
43.2		 2vavJ-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 LEU A  49
THR A  50
TYR A 219
TYR A 249
PHE A 340
 None
 0.90A 2vavJ-2b61A:
43.2		 2vavJ-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
TYR A 249
GLN A 253
 None
 1.00A 2vavK-2b61A:
42.8		 2vavK-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
TYR A 249
PHE A 340
 None
 0.91A 2vavK-2b61A:
42.8		 2vavK-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 ARG A 212
TYR A 219
HIS A 337
ASP A 338
PHE A 340
 None
 0.86A 2vavL-2b61A:
43.1		 2vavL-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 THR A  50
ARG A 212
TYR A 219
HIS A 337
PHE A 340
 None
 0.68A 2vavL-2b61A:
43.1		 2vavL-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 THR A  50
TYR A 219
TYR A 249
HIS A 337
PHE A 340
 None
 0.84A 2vavL-2b61A:
43.1		 2vavL-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 TYR A 219
TYR A 249
HIS A 337
ASP A 338
PHE A 340
 None
 0.68A 2vavL-2b61A:
43.1		 2vavL-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 TYR A 219
TYR A 249
PHE A 172
HIS A 337
ASP A 338
 None
 0.94A 2vavL-2b61A:
43.1		 2vavL-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_A_CSCA1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
GLN A 253
 None
 1.13A 2vaxA-2b61A:
43.3		 2vaxA-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_A_CSCA1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
HIS A 337
PHE A 340
 None
 0.64A 2vaxA-2b61A:
43.3		 2vaxA-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_A_CSCA1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 LEU A  49
THR A  50
TYR A 219
TYR A 249
GLN A 253
 None
 1.15A 2vaxA-2b61A:
43.3		 2vaxA-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_A_CSCA1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 LEU A  49
THR A  50
TYR A 219
TYR A 249
HIS A 337
PHE A 340
 None
 0.74A 2vaxA-2b61A:
43.3		 2vaxA-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
HIS A 337
PHE A 340
 None
 0.61A 2vaxB-2b61A:
43.3		 2vaxB-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 LEU A  49
THR A  50
TYR A 219
TYR A 249
HIS A 337
PHE A 340
 None
 0.85A 2vaxB-2b61A:
43.3		 2vaxB-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_C_CSCC1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 THR A  50
ARG A 212
TYR A 219
TYR A 249
HIS A 337
PHE A 340
 None
 0.88A 2vaxC-2b61A:
43.4		 2vaxC-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_D_CSCD1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
TYR A 249
GLN A 253
 None
 1.12A 2vaxD-2b61A:
43.5		 2vaxD-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_D_CSCD1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		7 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
TYR A 249
HIS A 337
PHE A 340
 None
 0.85A 2vaxD-2b61A:
43.5		 2vaxD-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_E_CSCE1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
HIS A 337
PHE A 340
 None
 0.64A 2vaxE-2b61A:
43.2		 2vaxE-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_E_CSCE1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 LEU A  49
THR A  50
TYR A 219
TYR A 249
HIS A 337
PHE A 340
 None
 0.74A 2vaxE-2b61A:
43.2		 2vaxE-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_F_CSCF1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
GLN A 253
 None
 1.14A 2vaxF-2b61A:
43.3		 2vaxF-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_F_CSCF1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
HIS A 337
PHE A 340
 None
 0.70A 2vaxF-2b61A:
43.3		 2vaxF-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_F_CSCF1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 LEU A  49
THR A  50
TYR A 219
TYR A 249
HIS A 337
PHE A 340
 None
 0.86A 2vaxF-2b61A:
43.3		 2vaxF-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
HIS A 337
PHE A 340
 None
 0.73A 2vaxG-2b61A:
43.4		 2vaxG-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
GLN A 253
 None
 0.86A 2vaxH-2b61A:
43.4		 2vaxH-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
HIS A 337
PHE A 340
 None
 0.66A 2vaxH-2b61A:
43.4		 2vaxH-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 LEU A  49
THR A  50
TYR A 219
TYR A 249
GLN A 253
 None
 0.96A 2vaxH-2b61A:
43.4		 2vaxH-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 LEU A  49
THR A  50
TYR A 219
TYR A 249
HIS A 337
PHE A 340
 None
 0.82A 2vaxH-2b61A:
43.4		 2vaxH-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_I_CSCI1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
HIS A 337
PHE A 340
 None
 0.68A 2vaxI-2b61A:
43.4		 2vaxI-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_I_CSCI1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 LEU A  49
THR A  50
TYR A 219
TYR A 249
HIS A 337
PHE A 340
 None
 0.85A 2vaxI-2b61A:
43.4		 2vaxI-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
GLN A 253
 None
 1.01A 2vaxJ-2b61A:
43.3		 2vaxJ-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
HIS A 337
PHE A 340
 None
 0.64A 2vaxJ-2b61A:
43.3		 2vaxJ-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 LEU A  49
THR A  50
TYR A 219
TYR A 249
GLN A 253
 None
 1.07A 2vaxJ-2b61A:
43.3		 2vaxJ-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		6 / 12 LEU A  49
THR A  50
TYR A 219
TYR A 249
HIS A 337
PHE A 340
 None
 0.85A 2vaxJ-2b61A:
43.3		 2vaxJ-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		7 / 12 LEU A  49
THR A  50
ARG A 212
TYR A 219
GLN A 253
HIS A 337
PHE A 340
 None
 1.15A 2vaxK-2b61A:
43.3		 2vaxK-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		7 / 12 LEU A  49
THR A  50
TYR A 219
TYR A 249
GLN A 253
HIS A 337
PHE A 340
 None
 1.13A 2vaxK-2b61A:
43.3		 2vaxK-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 THR A  50
ARG A 212
TYR A 219
HIS A 337
PHE A 340
 None
 0.65A 2vaxL-2b61A:
43.1		 2vaxL-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 THR A  50
TYR A 219
TYR A 249
HIS A 337
PHE A 340
 None
 0.88A 2vaxL-2b61A:
43.1		 2vaxL-2b61A:
28.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 7 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.21A 2y69A-2b61A:
undetectable
2y69C-2b61A:
undetectable		 2y69A-2b61A:
21.56
2y69C-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_1
(WNT INHIBITORY
FACTOR 1)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 6 LEU A 355
ILE A 351
MET A  69
VAL A  27
 None
 0.95A 2ygoA-2b61A:
undetectable		 2ygoA-2b61A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 LEU A 273
SER A 168
SER A 169
VAL A 117
HIS A  47
 None
 1.21A 2zlcA-2b61A:
undetectable		 2zlcA-2b61A:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 6 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.23A 2zxwA-2b61A:
undetectable
2zxwC-2b61A:
1.6		 2zxwA-2b61A:
21.56
2zxwC-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 6 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.22A 2zxwN-2b61A:
undetectable
2zxwP-2b61A:
undetectable		 2zxwN-2b61A:
21.56
2zxwP-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 7 GLY A  96
SER A  99
VAL A 123
ILE A 115
 None
 0.71A 3a2qA-2b61A:
undetectable		 3a2qA-2b61A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 7 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.24A 3abkA-2b61A:
undetectable
3abkC-2b61A:
undetectable		 3abkA-2b61A:
21.56
3abkC-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 6 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.20A 3asnA-2b61A:
undetectable
3asnC-2b61A:
undetectable		 3asnA-2b61A:
21.56
3asnC-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 8 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.20A 3asoA-2b61A:
undetectable
3asoC-2b61A:
undetectable
3asoP-2b61A:
undetectable		 3asoA-2b61A:
21.56
3asoC-2b61A:
22.78
3asoP-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 8 ALA A 176
ILE A 177
ASN A 180
ARG A 184
 None
 0.70A 3fxrA-2b61A:
undetectable		 3fxrA-2b61A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		3 / 3 ILE A 133
PHE A  81
HIS A 130
 None
 0.68A 3h0aA-2b61A:
undetectable		 3h0aA-2b61A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 7 ASN A 180
LEU A 214
LEU A  49
PHE A 172
 None
 1.29A 3nk2X-2b61A:
undetectable		 3nk2X-2b61A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 TYR A 276
ALA A 149
GLY A 142
SER A 143
ALA A 153
 None
 1.33A 3ou7C-2b61A:
2.4		 3ou7C-2b61A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_A_EVPA1_1
(DNA TOPOISOMERASE
2-BETA)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 5 GLY A 354
ASP A 353
ARG A 352
GLN A 346
 None
 1.18A 3qx3A-2b61A:
1.6		 3qx3A-2b61A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_D_EVPD1_1
(DNA TOPOISOMERASE
2-BETA)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 5 GLY A 354
ASP A 353
ARG A 352
GLN A 346
 None
 1.16A 3qx3B-2b61A:
1.6		 3qx3B-2b61A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 8 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.20A 3wg7A-2b61A:
undetectable
3wg7C-2b61A:
undetectable
3wg7P-2b61A:
undetectable		 3wg7A-2b61A:
21.56
3wg7C-2b61A:
22.78
3wg7P-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 5 TRP A  65
GLY A 145
ALA A  48
PHE A 347
 None
 1.47A 3wqwA-2b61A:
undetectable		 3wqwA-2b61A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 8 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.19A 3x2qA-2b61A:
undetectable
3x2qC-2b61A:
undetectable
3x2qP-2b61A:
undetectable		 3x2qA-2b61A:
21.56
3x2qC-2b61A:
22.78
3x2qP-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 GLY A 141
GLY A 146
ILE A 139
ILE A  45
LEU A 355
 None
 1.11A 4mwzA-2b61A:
2.2		 4mwzA-2b61A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 6 ASP A 334
ALA A 339
THR A 221
THR A 303
 None
 1.49A 4w5rA-2b61A:
3.1		 4w5rA-2b61A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 6 ASP A 334
ALA A 339
THR A 221
THR A 303
 None
 1.45A 4w5tA-2b61A:
3.1		 4w5tA-2b61A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 6 LYS A  21
LEU A  16
ASN A 114
PRO A 113
 None
 1.43A 4yv5A-2b61A:
undetectable		 4yv5A-2b61A:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 6 ASP A 334
ALA A 339
THR A 221
THR A 303
 None
 1.42A 4z4cA-2b61A:
3.0		 4z4cA-2b61A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 6 ASP A 334
ALA A 339
THR A 221
THR A 303
 None
 1.46A 4z4fA-2b61A:
3.1		 4z4fA-2b61A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 5 ASP A 334
ALA A 339
THR A 221
THR A 303
 None
 1.46A 4z4gA-2b61A:
3.3		 4z4gA-2b61A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 6 ASP A 334
ALA A 339
THR A 221
THR A 303
 None
 1.47A 4z4iA-2b61A:
3.1		 4z4iA-2b61A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 8 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.22A 5b1aA-2b61A:
undetectable
5b1aC-2b61A:
undetectable
5b1aP-2b61A:
undetectable		 5b1aA-2b61A:
21.56
5b1aC-2b61A:
22.78
5b1aP-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 7 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.19A 5iy5A-2b61A:
undetectable
5iy5C-2b61A:
1.7		 5iy5A-2b61A:
21.56
5iy5C-2b61A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MRA_B_DM2B204_1
(SORCIN)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 6 TYR A 243
THR A 233
ASP A 242
GLY A 241
 None
 1.16A 5mraA-2b61A:
undetectable
5mraB-2b61A:
0.4		 5mraA-2b61A:
17.29
5mraB-2b61A:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 7 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.21A 5wauC-2b61A:
undetectable
5waua-2b61A:
undetectable
5wauc-2b61A:
undetectable		 5wauC-2b61A:
22.78
5waua-2b61A:
21.56
5wauc-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 8 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.20A 5xdqA-2b61A:
undetectable
5xdqC-2b61A:
undetectable
5xdqP-2b61A:
undetectable		 5xdqA-2b61A:
21.56
5xdqC-2b61A:
22.78
5xdqP-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 8 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.21A 5z84A-2b61A:
undetectable
5z84C-2b61A:
undetectable
5z84P-2b61A:
undetectable		 5z84A-2b61A:
21.56
5z84C-2b61A:
22.78
5z84P-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 8 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.19A 5z85A-2b61A:
undetectable
5z85C-2b61A:
undetectable
5z85P-2b61A:
undetectable		 5z85A-2b61A:
21.56
5z85C-2b61A:
22.78
5z85P-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 8 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.18A 5z86A-2b61A:
undetectable
5z86C-2b61A:
undetectable
5z86P-2b61A:
undetectable		 5z86A-2b61A:
21.56
5z86C-2b61A:
22.78
5z86P-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 8 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.20A 5zcoA-2b61A:
undetectable
5zcoC-2b61A:
undetectable
5zcoP-2b61A:
undetectable		 5zcoA-2b61A:
21.56
5zcoC-2b61A:
22.78
5zcoP-2b61A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2b61 HOMOSERINE
O-ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 6 ASP A  78
THR A  77
TYR A  80
TRP A  65
 None
 1.19A 6nmpA-2b61A:
undetectable
6nmpC-2b61A:
1.6		 6nmpA-2b61A:
21.56
6nmpC-2b61A:
22.78