SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2b71'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2b71 CYCLOPHILIN-LIKE
PROTEIN
(Plasmodium
yoelii) 		4 / 8 ILE A  43
PHE A  66
GLY A  91
GLY A  92
 None
 0.80A 2qx4A-2b71A:
undetectable
2qx4B-2b71A:
undetectable		 2qx4A-2b71A:
23.05
2qx4B-2b71A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 2b71 CYCLOPHILIN-LIKE
PROTEIN
(Plasmodium
yoelii) 		4 / 7 LEU A 125
PHE A  66
ILE A 186
GLY A 123
 None
 0.94A 2v0mC-2b71A:
undetectable		 2v0mC-2b71A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA300_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 2b71 CYCLOPHILIN-LIKE
PROTEIN
(Plasmodium
yoelii) 		4 / 6 TYR A  75
CYH A  70
VAL A  52
PHE A 139
 None
 1.28A 3ltwA-2b71A:
undetectable		 3ltwA-2b71A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		 2b71 CYCLOPHILIN-LIKE
PROTEIN
(Plasmodium
yoelii) 		4 / 6 CYH A 165
THR A 164
ASN A 162
ILE A 141
 None
 1.37A 3w9tB-2b71A:
undetectable		 3w9tB-2b71A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_2
(SUGAR KINASE PROTEIN)		 2b71 CYCLOPHILIN-LIKE
PROTEIN
(Plasmodium
yoelii) 		4 / 4 SER A 136
TYR A 108
GLY A 100
PRO A  94
 None
 1.49A 4e3aA-2b71A:
undetectable		 4e3aA-2b71A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 2b71 CYCLOPHILIN-LIKE
PROTEIN
(Plasmodium
yoelii) 		3 / 3 SER A 136
TYR A 108
PRO A  94
 None
 0.95A 4k8cA-2b71A:
undetectable		 4k8cA-2b71A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2b71 CYCLOPHILIN-LIKE
PROTEIN
(Plasmodium
yoelii) 		3 / 3 SER A 136
TYR A 108
PRO A  94
 None
 0.94A 4kahA-2b71A:
undetectable		 4kahA-2b71A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2b71 CYCLOPHILIN-LIKE
PROTEIN
(Plasmodium
yoelii) 		3 / 3 SER A 136
TYR A 108
PRO A  94
 None
 0.94A 4kahB-2b71A:
undetectable		 4kahB-2b71A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2b71 CYCLOPHILIN-LIKE
PROTEIN
(Plasmodium
yoelii) 		3 / 3 SER A 136
TYR A 108
PRO A  94
 None
 0.95A 4kanA-2b71A:
undetectable		 4kanA-2b71A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2b71 CYCLOPHILIN-LIKE
PROTEIN
(Plasmodium
yoelii) 		3 / 3 SER A 136
TYR A 108
PRO A  94
 None
 0.97A 4kanB-2b71A:
undetectable		 4kanB-2b71A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2b71 CYCLOPHILIN-LIKE
PROTEIN
(Plasmodium
yoelii) 		3 / 3 SER A 136
TYR A 108
PRO A  94
 None
 0.96A 4kbeA-2b71A:
undetectable		 4kbeA-2b71A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2b71 CYCLOPHILIN-LIKE
PROTEIN
(Plasmodium
yoelii) 		3 / 3 SER A 136
TYR A 108
PRO A  94
 None
 0.94A 4kbeB-2b71A:
undetectable		 4kbeB-2b71A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2b71 CYCLOPHILIN-LIKE
PROTEIN
(Plasmodium
yoelii) 		3 / 3 SER A 136
TYR A 108
PRO A  94
 None
 0.97A 4lbgA-2b71A:
undetectable		 4lbgA-2b71A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2b71 CYCLOPHILIN-LIKE
PROTEIN
(Plasmodium
yoelii) 		3 / 3 SER A 136
TYR A 108
PRO A  94
 None
 0.95A 4lbgB-2b71A:
undetectable		 4lbgB-2b71A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2b71 CYCLOPHILIN-LIKE
PROTEIN
(Plasmodium
yoelii) 		5 / 12 LEU A 125
PHE A  66
ILE A 141
GLY A  91
THR A  78
 None
 1.15A 4nkvA-2b71A:
undetectable		 4nkvA-2b71A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2b71 CYCLOPHILIN-LIKE
PROTEIN
(Plasmodium
yoelii) 		5 / 12 LEU A 125
PHE A  66
ILE A 141
GLY A  91
THR A  78
 None
 1.16A 4nkvC-2b71A:
undetectable		 4nkvC-2b71A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2b71 CYCLOPHILIN-LIKE
PROTEIN
(Plasmodium
yoelii) 		5 / 12 LEU A 125
PHE A  66
ILE A 141
GLY A  91
THR A  78
 None
 1.15A 4nkvD-2b71A:
undetectable		 4nkvD-2b71A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDZ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2b71 CYCLOPHILIN-LIKE
PROTEIN
(Plasmodium
yoelii) 		4 / 7 PHE A  66
ILE A  41
PHE A 139
THR A  78
 None
 0.95A 4zdzA-2b71A:
undetectable		 4zdzA-2b71A:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESF_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2b71 CYCLOPHILIN-LIKE
PROTEIN
(Plasmodium
yoelii) 		4 / 8 PHE A  66
ILE A  41
PHE A 139
THR A  78
 None
 0.93A 5esfA-2b71A:
undetectable		 5esfA-2b71A:
15.77