SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2b7h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 2b7h HEMOGLOBIN BETA
CHAIN
(Cerdocyon
thous) 		4 / 8 SER B  72
SER B  70
ASN B  69
THR B  84
 None
HEM  B 200 (-3.3A)
None
None
 1.08A 1ig3A-2b7hB:
undetectable
1ig3B-2b7hB:
undetectable		 1ig3A-2b7hB:
20.00
1ig3B-2b7hB:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 6 ALA A  57
ASP A  64
ALA A  65
LEU A  83
 None
None
HEM  A 200 ( 3.7A)
HEM  A 200 (-4.2A)
 0.44A 1iwhA-2b7hA:
27.0		 1iwhA-2b7hA:
81.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 8 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.95A 1iwiA-2b7hA:
undetectable		 1iwiA-2b7hA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 7 PHE A  43
PHE A  46
VAL A  62
HIS A  87
 HEM  A 200 (-3.5A)
HEM  A 200 (-4.6A)
HEM  A 200 ( 3.8A)
HEM  A 200 (-3.2A)
 0.97A 1lh6A-2b7hA:
13.4		 1lh6A-2b7hA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 2b7h HEMOGLOBIN BETA
CHAIN
(Cerdocyon
thous) 		4 / 7 PHE B  42
PHE B  45
VAL B  67
HIS B  92
 HEM  B 200 (-4.1A)
None
HEM  B 200 ( 3.8A)
HEM  B 200 (-3.2A)
 0.83A 1lh6A-2b7hB:
13.8		 1lh6A-2b7hB:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2b7h HEMOGLOBIN ALPHA
CHAIN
HEMOGLOBIN BETA
CHAIN
(Cerdocyon
thous) 		4 / 5 LEU B 105
VAL B 109
CYH B 112
ALA A 110
 None
 1.13A 1mz9D-2b7hB:
undetectable		 1mz9D-2b7hB:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2b7h HEMOGLOBIN ALPHA
CHAIN
HEMOGLOBIN BETA
CHAIN
(Cerdocyon
thous) 		4 / 4 LEU B 105
VAL B 109
CYH B 112
ALA A 110
 None
 1.11A 1mz9E-2b7hB:
undetectable		 1mz9E-2b7hB:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 7 THR A  39
PHE A  33
PHE A  98
LEU A 105
 HEM  A 200 ( 4.5A)
None
HEM  A 200 (-3.8A)
None
 1.10A 1qcaA-2b7hA:
undetectable		 1qcaA-2b7hA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 7 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.96A 1t85A-2b7hA:
undetectable		 1t85A-2b7hA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 7 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.94A 1t87A-2b7hA:
undetectable		 1t87A-2b7hA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 7 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.97A 1t87B-2b7hA:
undetectable		 1t87B-2b7hA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		5 / 12 GLY A  25
GLY A  26
PHE A  43
PHE A  33
HIS A  58
 None
None
HEM  A 200 (-3.5A)
None
HEM  A 200 (-4.0A)
 0.93A 1w6rA-2b7hA:
undetectable		 1w6rA-2b7hA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 7 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.92A 1yrcA-2b7hA:
undetectable		 1yrcA-2b7hA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 7 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.95A 1yrdA-2b7hA:
undetectable		 1yrdA-2b7hA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2002_1
(SERUM ALBUMIN)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		5 / 11 ALA A  69
LEU A  76
SER A  84
LEU A 136
VAL A 135
 None
None
None
HEM  A 200 (-4.8A)
None
 1.09A 2bxeB-2b7hA:
2.1		 2bxeB-2b7hA:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 6 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.95A 2feuA-2b7hA:
undetectable		 2feuA-2b7hA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 7 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.91A 2feuB-2b7hA:
undetectable		 2feuB-2b7hA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2b7h HEMOGLOBIN BETA
CHAIN
(Cerdocyon
thous) 		5 / 12 GLY B  83
LEU B  75
GLY B  74
LEU B  78
LEU B   3
 None
 0.93A 2nxeA-2b7hB:
undetectable		 2nxeA-2b7hB:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 8 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.87A 2qbmA-2b7hA:
undetectable		 2qbmA-2b7hA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_X_CPFX1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 4 ARG A  31
GLY A  25
GLU A  27
SER A 133
 None
None
None
HEM  A 200 ( 4.8A)
 1.09A 2xctS-2b7hA:
undetectable
2xctU-2b7hA:
undetectable		 2xctS-2b7hA:
12.86
2xctU-2b7hA:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 6 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 1.00A 2zuhA-2b7hA:
undetectable		 2zuhA-2b7hA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 6 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.93A 2zuiA-2b7hA:
undetectable		 2zuiA-2b7hA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 7 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.94A 2zwtA-2b7hA:
undetectable		 2zwtA-2b7hA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 7 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.93A 2zwuA-2b7hA:
undetectable		 2zwuA-2b7hA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 7 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.92A 3fwfA-2b7hA:
undetectable		 3fwfA-2b7hA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 7 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.95A 3fwfB-2b7hA:
undetectable		 3fwfB-2b7hA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 7 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.92A 3fwiA-2b7hA:
undetectable		 3fwiA-2b7hA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 7 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.94A 3fwjA-2b7hA:
undetectable		 3fwjA-2b7hA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 7 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.94A 3l63A-2b7hA:
undetectable		 3l63A-2b7hA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		3 / 3 PHE A  46
SER A  52
GLN A  54
 HEM  A 200 (-4.6A)
None
None
 0.73A 3smtA-2b7hA:
1.2		 3smtA-2b7hA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 7 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.93A 3wrhA-2b7hA:
undetectable		 3wrhA-2b7hA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 7 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.93A 3wrjA-2b7hA:
undetectable		 3wrjA-2b7hA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 7 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.93A 3wrlA-2b7hA:
undetectable		 3wrlA-2b7hA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 7 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.93A 3wrlE-2b7hA:
undetectable		 3wrlE-2b7hA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 7 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.94A 3wrmA-2b7hA:
undetectable		 3wrmA-2b7hA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 7 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.94A 3wrmF-2b7hA:
undetectable		 3wrmF-2b7hA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLA_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 8 LEU A 109
LEU A 105
LEU A 101
ILE A  17
 None
None
HEM  A 200 (-4.4A)
None
 0.87A 4klaA-2b7hA:
undetectable		 4klaA-2b7hA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 8 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.99A 4l4aA-2b7hA:
undetectable		 4l4aA-2b7hA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 7 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.92A 4l4gA-2b7hA:
undetectable		 4l4gA-2b7hA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		5 / 11 LEU A 109
ILE A  10
SER A  12
PHE A 129
LEU A  73
 None
 1.48A 4lhmA-2b7hA:
undetectable		 4lhmA-2b7hA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 8 LEU A 109
LEU A 106
ASP A   6
ILE A  10
 None
 0.79A 4lzrA-2b7hA:
undetectable		 4lzrA-2b7hA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 2b7h HEMOGLOBIN ALPHA
CHAIN
HEMOGLOBIN BETA
CHAIN
(Cerdocyon
thous) 		4 / 8 VAL A  96
LEU A 100
GLN B 131
VAL B 134
 None
 0.79A 4ma7A-2b7hA:
2.9		 4ma7A-2b7hA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 2b7h HEMOGLOBIN BETA
CHAIN
(Cerdocyon
thous) 		5 / 10 PRO B 124
VAL B 126
ALA B 128
TYR B 130
GLY B 119
 None
 1.35A 4mmdA-2b7hB:
undetectable		 4mmdA-2b7hB:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 4 LEU A  76
SER A 133
LEU A  66
LEU A   2
 None
HEM  A 200 ( 4.8A)
HEM  A 200 ( 4.6A)
None
 0.91A 4n09A-2b7hA:
undetectable		 4n09A-2b7hA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 5 LEU A  76
SER A 133
LEU A  66
LEU A   2
 None
HEM  A 200 ( 4.8A)
HEM  A 200 ( 4.6A)
None
 0.91A 4n09B-2b7hA:
undetectable		 4n09B-2b7hA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 5 LEU A  76
SER A 133
LEU A  66
LEU A   2
 None
HEM  A 200 ( 4.8A)
HEM  A 200 ( 4.6A)
None
 0.91A 4n09D-2b7hA:
undetectable		 4n09D-2b7hA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2b7h HEMOGLOBIN BETA
CHAIN
(Cerdocyon
thous) 		4 / 8 LEU B 110
VAL B 137
TYR B 130
TRP B  15
 None
 1.04A 4puoC-2b7hB:
undetectable		 4puoC-2b7hB:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		5 / 12 LEU A   2
LEU A  76
ALA A 131
SER A 102
ILE A  10
 None
 1.03A 5h8tA-2b7hA:
undetectable		 5h8tA-2b7hA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2b7h HEMOGLOBIN BETA
CHAIN
(Cerdocyon
thous) 		4 / 4 VAL B 133
VAL B 134
TYR B 130
GLN B 127
 None
 1.21A 5qggA-2b7hB:
undetectable		 5qggA-2b7hB:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGO_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2b7h HEMOGLOBIN BETA
CHAIN
(Cerdocyon
thous) 		4 / 4 VAL B 133
VAL B 134
TYR B 130
GLN B 127
 None
 1.18A 5qgoA-2b7hB:
undetectable		 5qgoA-2b7hB:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2b7h HEMOGLOBIN BETA
CHAIN
(Cerdocyon
thous) 		4 / 4 VAL B 133
VAL B 134
TYR B 130
GLN B 127
 None
 1.18A 5qgpA-2b7hB:
undetectable		 5qgpA-2b7hB:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGQ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2b7h HEMOGLOBIN BETA
CHAIN
(Cerdocyon
thous) 		4 / 4 VAL B 133
VAL B 134
TYR B 130
GLN B 127
 None
 1.25A 5qgqA-2b7hB:
undetectable		 5qgqA-2b7hB:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHB_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2b7h HEMOGLOBIN BETA
CHAIN
(Cerdocyon
thous) 		4 / 4 VAL B 133
VAL B 134
TYR B 130
GLN B 127
 None
 1.22A 5qhbA-2b7hB:
undetectable		 5qhbA-2b7hB:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2b7h HEMOGLOBIN ALPHA
CHAIN
(Cerdocyon
thous) 		4 / 7 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.96A 5wk9A-2b7hA:
undetectable		 5wk9A-2b7hA:
17.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X2S_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 2b7h HEMOGLOBIN ALPHA
CHAIN
HEMOGLOBIN BETA
CHAIN
(Cerdocyon
thous) 		5 / 8 PRO A  95
THR A 134
THR A 137
TYR A 140
TRP B  37
 None
 0.62A 5x2sI-2b7hA:
25.7
5x2sJ-2b7hA:
21.9
5x2sK-2b7hA:
26.4		 5x2sI-2b7hA:
82.98
5x2sJ-2b7hA:
43.24
5x2sK-2b7hA:
82.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 2b7h HEMOGLOBIN ALPHA
CHAIN
HEMOGLOBIN BETA
CHAIN
(Cerdocyon
thous) 		4 / 8 PRO A  95
THR A 134
THR A 137
TRP B  37
 None
 0.55A 5x2tI-2b7hA:
25.9
5x2tJ-2b7hA:
21.9
5x2tK-2b7hA:
26.3
5x2tL-2b7hA:
20.1		 5x2tI-2b7hA:
82.98
5x2tJ-2b7hA:
43.24
5x2tK-2b7hA:
82.98
5x2tL-2b7hA:
43.24