SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2b7y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRD_A_MIYA2001_1
(ACRB)		 2b7y FAVIN BETA CHAIN
(Vicia
faba) 		5 / 9 GLY A 158
GLU A 160
ILE A  72
ALA A  74
VAL A  80
 None
 1.15A 2drdA-2b7yA:
undetectable		 2drdA-2b7yA:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2b7y FAVIN BETA CHAIN
(Vicia
faba) 		4 / 6 HIS A 137
VAL A 176
ILE A 145
LEU A 174
 MN  A 501 (-3.3A)
None
None
None
 0.88A 3kk6A-2b7yA:
undetectable		 3kk6A-2b7yA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 2b7y FAVIN BETA CHAIN
FAVIN ALPHA CHAIN
(Vicia
faba;
Vicia
faba) 		5 / 12 THR A  93
ILE A  53
ILE A  88
VAL B 198
PRO B 199
 None
 1.09A 3kpdC-2b7yA:
undetectable		 3kpdC-2b7yA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 2b7y FAVIN ALPHA CHAIN
FAVIN BETA CHAIN
(Vicia
faba) 		4 / 8 SER B 189
ALA A 164
SER A 175
THR A 177
 None
 0.34A 4ikjA-2b7yB:
undetectable
4ikjB-2b7yB:
undetectable		 4ikjA-2b7yB:
16.41
4ikjB-2b7yB:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)		 2b7y FAVIN ALPHA CHAIN
FAVIN BETA CHAIN
(Vicia
faba) 		4 / 8 ALA A 164
SER A 175
THR A 177
SER B 189
 None
 0.39A 4ikkA-2b7yA:
undetectable
4ikkB-2b7yA:
undetectable		 4ikkA-2b7yA:
21.43
4ikkB-2b7yA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 2b7y FAVIN ALPHA CHAIN
FAVIN BETA CHAIN
(Vicia
faba) 		4 / 8 SER B 189
ALA A 164
SER A 175
THR A 177
 None
 0.47A 4iklA-2b7yB:
undetectable
4iklB-2b7yB:
undetectable		 4iklA-2b7yB:
16.41
4iklB-2b7yB:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2b7y FAVIN BETA CHAIN
(Vicia
faba) 		3 / 3 PHE A  64
ILE A  53
ASP A   2
 None
 0.76A 5cswB-2b7yA:
undetectable		 5cswB-2b7yA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 2b7y FAVIN BETA CHAIN
FAVIN ALPHA CHAIN
(Vicia
faba;
Vicia
faba) 		4 / 5 LEU A 102
THR B 209
THR A  97
GLY A  99
 None
None
None
GLC  A 801 (-3.2A)
 1.24A 6gtqA-2b7yA:
undetectable		 6gtqA-2b7yA:
23.12