SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2b87'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F86_B_T44B528_1
(TRANSTHYRETIN
THR119MET VARIANT)		 2b87 ANTI-ZTAQ AFFIBODY
(Staphylococcus
aureus) 		4 / 4 LYS B  49
LEU B  45
ALA B  48
LEU B  44
 None
 1.37A 1f86B-2b87B:
undetectable		 1f86B-2b87B:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2b87 ANTI-ZTAQ AFFIBODY
ZTAQ AFFIBODY
(Staphylococcus
aureus) 		4 / 6 ILE B  13
TRP A  14
PHE A  17
GLU A  15
 None
 1.40A 1nsiA-2b87B:
undetectable
1nsiB-2b87B:
undetectable		 1nsiA-2b87B:
8.25
1nsiB-2b87B:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2b87 ANTI-ZTAQ AFFIBODY
ZTAQ AFFIBODY
(Staphylococcus
aureus) 		4 / 6 TRP A  14
PHE A  17
GLU A  15
ILE B  13
 None
 1.45A 1nsiA-2b87A:
undetectable
1nsiB-2b87A:
undetectable		 1nsiA-2b87A:
8.73
1nsiB-2b87A:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2b87 ANTI-ZTAQ AFFIBODY
ZTAQ AFFIBODY
(Staphylococcus
aureus) 		4 / 6 ILE B  13
TRP A  14
PHE A  17
GLU A  15
 None
 1.39A 1nsiC-2b87B:
undetectable
1nsiD-2b87B:
undetectable		 1nsiC-2b87B:
8.25
1nsiD-2b87B:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2b87 ANTI-ZTAQ AFFIBODY
ZTAQ AFFIBODY
(Staphylococcus
aureus) 		4 / 6 TRP A  14
PHE A  17
GLU A  15
ILE B  13
 None
 1.39A 1nsiC-2b87A:
undetectable
1nsiD-2b87A:
undetectable		 1nsiC-2b87A:
8.73
1nsiD-2b87A:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2b87 ANTI-ZTAQ AFFIBODY
ZTAQ AFFIBODY
(Staphylococcus
aureus) 		4 / 7 ILE B  13
TRP A  14
PHE A  17
GLU A  15
 None
 1.38A 2nsiA-2b87B:
undetectable
2nsiB-2b87B:
undetectable		 2nsiA-2b87B:
8.25
2nsiB-2b87B:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2b87 ANTI-ZTAQ AFFIBODY
ZTAQ AFFIBODY
(Staphylococcus
aureus) 		4 / 7 TRP A  14
PHE A  17
GLU A  15
ILE B  13
 None
 1.37A 2nsiA-2b87A:
undetectable
2nsiB-2b87A:
undetectable		 2nsiA-2b87A:
8.73
2nsiB-2b87A:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2b87 ANTI-ZTAQ AFFIBODY
ZTAQ AFFIBODY
(Staphylococcus
aureus) 		4 / 7 ILE B  13
TRP A  14
PHE A  17
GLU A  15
 None
 1.36A 2nsiC-2b87B:
undetectable
2nsiD-2b87B:
undetectable		 2nsiC-2b87B:
8.25
2nsiD-2b87B:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2b87 ANTI-ZTAQ AFFIBODY
ZTAQ AFFIBODY
(Staphylococcus
aureus) 		4 / 7 TRP A  14
PHE A  17
GLU A  15
ILE B  13
 None
 1.38A 2nsiC-2b87A:
undetectable
2nsiD-2b87A:
undetectable		 2nsiC-2b87A:
8.73
2nsiD-2b87A:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2b87 ANTI-ZTAQ AFFIBODY
ZTAQ AFFIBODY
(Staphylococcus
aureus) 		4 / 7 ILE B  13
TRP A  14
PHE A  17
GLU A  15
 None
 1.38A 3e7gA-2b87B:
undetectable
3e7gB-2b87B:
undetectable		 3e7gA-2b87B:
8.79
3e7gB-2b87B:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_B_H4BB1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2b87 ANTI-ZTAQ AFFIBODY
ZTAQ AFFIBODY
(Staphylococcus
aureus) 		4 / 7 TRP A  14
PHE A  17
GLU A  15
ILE B  13
 None
 1.38A 3e7gA-2b87A:
undetectable
3e7gB-2b87A:
undetectable		 3e7gA-2b87A:
9.03
3e7gB-2b87A:
9.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_C_H4BC2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2b87 ANTI-ZTAQ AFFIBODY
ZTAQ AFFIBODY
(Staphylococcus
aureus) 		4 / 7 ILE B  13
TRP A  14
PHE A  17
GLU A  15
 None
 1.39A 3e7gC-2b87B:
undetectable
3e7gD-2b87B:
undetectable		 3e7gC-2b87B:
8.79
3e7gD-2b87B:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2b87 ANTI-ZTAQ AFFIBODY
ZTAQ AFFIBODY
(Staphylococcus
aureus) 		4 / 8 TRP A  14
PHE A  17
GLU A  15
ILE B  13
 None
 1.36A 3e7gC-2b87A:
undetectable
3e7gD-2b87A:
undetectable		 3e7gC-2b87A:
9.03
3e7gD-2b87A:
9.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 2b87 ZTAQ AFFIBODY
ANTI-ZTAQ AFFIBODY
(Staphylococcus
aureus;
Staphylococcus
aureus) 		3 / 3 LYS B   1
ARG B   9
LYS A  49
 None
 1.46A 3okxA-2b87B:
undetectable		 3okxA-2b87B:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_D_H4BD600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2b87 ANTI-ZTAQ AFFIBODY
ZTAQ AFFIBODY
(Staphylococcus
aureus) 		4 / 7 TRP A  14
PHE A  17
GLU A  15
ILE B  13
 None
 1.40A 4cx7C-2b87A:
undetectable
4cx7D-2b87A:
undetectable		 4cx7C-2b87A:
8.73
4cx7D-2b87A:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2b87 ZTAQ AFFIBODY
ANTI-ZTAQ AFFIBODY
(Staphylococcus
aureus;
Staphylococcus
aureus) 		4 / 6 GLY B  14
GLY A  10
GLU B  15
ILE B  11
 None
 0.98A 4fglD-2b87B:
undetectable		 4fglD-2b87B:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_B_H4BB1011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 2b87 ANTI-ZTAQ AFFIBODY
ZTAQ AFFIBODY
(Staphylococcus
aureus) 		4 / 7 TRP A  14
PHE A  17
GLU A  15
ILE B  13
 None
 1.31A 4nosA-2b87A:
undetectable
4nosB-2b87A:
undetectable		 4nosA-2b87A:
9.44
4nosB-2b87A:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_C_H4BC2011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 2b87 ANTI-ZTAQ AFFIBODY
ZTAQ AFFIBODY
(Staphylococcus
aureus) 		4 / 7 ILE B  13
TRP A  14
PHE A  17
GLU A  15
 None
 1.36A 4nosC-2b87B:
undetectable
4nosD-2b87B:
undetectable		 4nosC-2b87B:
8.79
4nosD-2b87B:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_D_H4BD3011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 2b87 ANTI-ZTAQ AFFIBODY
ZTAQ AFFIBODY
(Staphylococcus
aureus) 		4 / 6 TRP A  14
PHE A  17
GLU A  15
ILE B  13
 None
 1.36A 4nosC-2b87A:
undetectable
4nosD-2b87A:
undetectable		 4nosC-2b87A:
9.44
4nosD-2b87A:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2b87 ANTI-ZTAQ AFFIBODY
ZTAQ AFFIBODY
(Staphylococcus
aureus) 		3 / 3 VAL A   1
LEU A  34
MET B  17
 None
 0.85A 5ikrA-2b87A:
undetectable		 5ikrA-2b87A:
8.56