SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2b9c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_1
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2b9c STRIATED-MUSCLE
ALPHA TROPOMYOSIN
(Rattus
norvegicus) 		4 / 4 ILE A 172
LEU A 169
VAL A 165
ALA A 158
 None
 0.98A 1mz9A-2b9cA:
3.8		 1mz9A-2b9cA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2b9c STRIATED-MUSCLE
ALPHA TROPOMYOSIN
(Rattus
norvegicus) 		4 / 5 ILE A 172
LEU A 169
VAL A 165
ALA A 158
 None
 0.98A 1mz9C-2b9cA:
3.8		 1mz9C-2b9cA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2b9c STRIATED-MUSCLE
ALPHA TROPOMYOSIN
(Rattus
norvegicus) 		3 / 3 LEU A 197
VAL A 200
LEU A 204
 None
 0.36A 1mz9B-2b9cA:
undetectable		 1mz9B-2b9cA:
15.65