SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2b9l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 2b9l PROPHENOLOXIDASE
ACTIVATING FACTOR
(Holotrichia
diomphalia) 		4 / 4 ILE A  29
MET A  24
VAL A 194
GLY A  31
 None
None
None
NAG  A 416 ( 4.6A)
 1.30A 1e06B-2b9lA:
undetectable		 1e06B-2b9lA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 2b9l PROPHENOLOXIDASE
ACTIVATING FACTOR
(Holotrichia
diomphalia) 		4 / 6 ALA A 191
LEU A 196
SER A 188
THR A 270
 None
 0.93A 1ictB-2b9lA:
undetectable		 1ictB-2b9lA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 2b9l PROPHENOLOXIDASE
ACTIVATING FACTOR
(Holotrichia
diomphalia) 		3 / 3 GLY A  59
GLU A 104
ASP A  63
 None
 0.61A 2b25B-2b9lA:
undetectable		 2b25B-2b9lA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFX_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 2b9l PROPHENOLOXIDASE
ACTIVATING FACTOR
(Holotrichia
diomphalia) 		5 / 8 LEU A 183
ALA A 168
GLY A 289
LEU A 305
ASP A 220
 None
 1.29A 2yfxA-2b9lA:
undetectable		 2yfxA-2b9lA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		 2b9l PROPHENOLOXIDASE
ACTIVATING FACTOR
(Holotrichia
diomphalia) 		5 / 8 VAL A 195
GLY A 198
THR A 197
PHE A 244
ALA A 254
 None
 1.30A 3aruA-2b9lA:
undetectable		 3aruA-2b9lA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 2b9l PROPHENOLOXIDASE
ACTIVATING FACTOR
(Holotrichia
diomphalia) 		3 / 3 GLY A 289
GLY A 353
GLY A 351
 None
SO4  A 424 ( 4.3A)
None
 0.39A 3bogC-2b9lA:
undetectable		 3bogC-2b9lA:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_A_DIFA1_1
(TRANSTHYRETIN)		 2b9l PROPHENOLOXIDASE
ACTIVATING FACTOR
(Holotrichia
diomphalia) 		4 / 6 ALA A 191
LEU A 196
SER A 188
THR A 270
 None
 1.01A 3cfqA-2b9lA:
undetectable		 3cfqA-2b9lA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2b9l PROPHENOLOXIDASE
ACTIVATING FACTOR
(Holotrichia
diomphalia) 		5 / 12 LEU A 273
VAL A 169
GLY A 217
LEU A 262
ILE A 268
 None
 1.01A 3ku1H-2b9lA:
undetectable		 3ku1H-2b9lA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2b9l PROPHENOLOXIDASE
ACTIVATING FACTOR
(Holotrichia
diomphalia) 		5 / 12 ILE A 190
ALA A 254
THR A 197
VAL A 194
VAL A 195
 None
 1.02A 3rukB-2b9lA:
undetectable		 3rukB-2b9lA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)		 2b9l PROPHENOLOXIDASE
ACTIVATING FACTOR
(Holotrichia
diomphalia) 		5 / 12 ALA A 199
GLN A 206
ASN A 203
ILE A 235
LEU A 196
 None
 1.23A 4azwA-2b9lA:
undetectable		 4azwA-2b9lA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA503_1
(PENTALENIC ACID
SYNTHASE)		 2b9l PROPHENOLOXIDASE
ACTIVATING FACTOR
(Holotrichia
diomphalia) 		5 / 7 LEU A 209
ALA A 254
LEU A 256
LEU A 257
ILE A 240
 None
 1.04A 4ubsA-2b9lA:
undetectable		 4ubsA-2b9lA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 2b9l PROPHENOLOXIDASE
ACTIVATING FACTOR
(Holotrichia
diomphalia) 		4 / 6 LEU A 305
ILE A 304
LYS A 307
GLU A 162
 None
 0.79A 4w5nA-2b9lA:
undetectable		 4w5nA-2b9lA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 2b9l PROPHENOLOXIDASE
ACTIVATING FACTOR
(Holotrichia
diomphalia) 		5 / 12 GLY A 198
GLY A 354
SER A 355
GLY A 187
LEU A 196
 None
 0.85A 5c0oH-2b9lA:
undetectable		 5c0oH-2b9lA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2b9l PROPHENOLOXIDASE
ACTIVATING FACTOR
(Holotrichia
diomphalia) 		5 / 12 ILE A 373
GLY A 354
SER A 242
ILE A 240
PHE A 244
 None
 1.41A 5igwA-2b9lA:
undetectable		 5igwA-2b9lA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 2b9l PROPHENOLOXIDASE
ACTIVATING FACTOR
(Holotrichia
diomphalia) 		4 / 8 LEU A 257
VAL A 195
LEU A 209
ILE A 214
 None
 0.89A 5v0vA-2b9lA:
undetectable		 5v0vA-2b9lA:
19.15