SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2b9u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2b9u HYPOTHETICAL
DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Sulfurisphaera
tokodaii) 		4 / 7 VAL A 128
SER A  50
ARG A  58
HIS A  61
 None
 0.96A 2f78A-2b9uA:
undetectable		 2f78A-2b9uA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2b9u HYPOTHETICAL
DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Sulfurisphaera
tokodaii) 		4 / 6 VAL A 128
SER A  50
ARG A  58
HIS A  61
 None
 0.86A 2f8dA-2b9uA:
undetectable		 2f8dA-2b9uA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_1
(PROTEASE)		 2b9u HYPOTHETICAL
DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Sulfurisphaera
tokodaii) 		5 / 12 LEU A   8
ALA A  84
GLY A  70
ILE A  72
ILE A  12
 None
 1.08A 2o4kA-2b9uA:
undetectable		 2o4kA-2b9uA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 2b9u HYPOTHETICAL
DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Sulfurisphaera
tokodaii) 		5 / 12 ILE A 112
GLY A 119
ASP A  86
VAL A  87
ARG A  88
 None
 0.84A 2qe6A-2b9uA:
undetectable		 2qe6A-2b9uA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2b9u HYPOTHETICAL
DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Sulfurisphaera
tokodaii) 		3 / 3 GLY A  55
PRO A 153
LEU A 123
 None
 0.64A 3hcpB-2b9uA:
undetectable		 3hcpB-2b9uA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_2
(DIHYDROFOLATE
REDUCTASE)		 2b9u HYPOTHETICAL
DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Sulfurisphaera
tokodaii) 		4 / 4 ILE A  72
PHE A  36
ILE A  15
THR A 133
 None
 1.10A 3ia4A-2b9uA:
undetectable		 3ia4A-2b9uA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2b9u HYPOTHETICAL
DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Sulfurisphaera
tokodaii) 		4 / 6 TYR A 130
GLN A  46
ILE A 132
SER A  50
 None
 1.16A 3pmzD-2b9uA:
undetectable		 3pmzD-2b9uA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		 2b9u HYPOTHETICAL
DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Sulfurisphaera
tokodaii) 		3 / 3 GLU A  68
PHE A 175
GLN A  63
 None
 0.93A 3r55A-2b9uA:
undetectable		 3r55A-2b9uA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 2b9u HYPOTHETICAL
DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Sulfurisphaera
tokodaii) 		4 / 7 ILE A 112
LEU A 110
ALA A  84
VAL A  85
 None
 0.82A 4g77A-2b9uA:
undetectable		 4g77A-2b9uA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P68_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 2b9u HYPOTHETICAL
DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Sulfurisphaera
tokodaii) 		5 / 11 ILE A  72
PHE A  36
LYS A  32
ILE A  15
THR A 133
 None
 1.36A 4p68A-2b9uA:
undetectable		 4p68A-2b9uA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_C_URFC301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 2b9u HYPOTHETICAL
DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Sulfurisphaera
tokodaii) 		3 / 3 ARG A 143
HIS A 141
ARG A  64
 None
 1.06A 5iaoC-2b9uA:
undetectable		 5iaoC-2b9uA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_F_URFF301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 2b9u HYPOTHETICAL
DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Sulfurisphaera
tokodaii) 		3 / 3 ARG A 143
HIS A 141
ARG A  64
 None
 1.05A 5iaoF-2b9uA:
undetectable		 5iaoF-2b9uA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB303_1
(BIFUNCTIONAL PROTEIN
FOLD)		 2b9u HYPOTHETICAL
DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Sulfurisphaera
tokodaii) 		4 / 5 TYR A 130
LYS A  71
GLY A  55
ILE A  80
 None
 1.27A 6debB-2b9uA:
undetectable		 6debB-2b9uA:
18.82