SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ba0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RX3_A_MTXA161_2 (DIHYDROFOLATE REDUCTASE)	2ba0	ARCHAEAL EXOSOME RNA BINDING PROTEIN RRP4 (Archaeoglobus fulgidus)	3 / 3	LYS A 2 ILE A 34 THR A 22	None	0.80A	1rx3A-2ba0A: undetectable	1rx3A-2ba0A: 21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GH8_A_MTXA201_2 (DIHYDROFOLATE REDUCTASE)	2ba0	ARCHAEAL EXOSOME RNA BINDING PROTEIN RRP4 (Archaeoglobus fulgidus)	3 / 3	LYS A 2 ILE A 34 THR A 22	None	0.86A	4gh8A-2ba0A: undetectable	4gh8A-2ba0A: 21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4N09_C_ADNC401_2 (ADENOSINE KINASE)	2ba0	ARCHAEAL EXOSOME RNA BINDING PROTEIN RRP4 (Archaeoglobus fulgidus)	4 / 5	ASN A 90 LEU A 85 SER A 88 LEU A 114	None	1.14A	4n09C-2ba0A: undetectable	4n09C-2ba0A: 19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EML_A_SAMA701_1 (PROTEIN ARGININE N-METHYLTRANSFERASE 5)	2ba0	ARCHAEAL EXOSOME RNA BINDING PROTEIN RRP4 (Archaeoglobus fulgidus)	4 / 6	TYR A 53 TYR A 20 GLY A 58 ASP A 128	None	1.04A	5emlA-2ba0A: undetectable	5emlA-2ba0A: 15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KB5_A_ADNA401_2 (ADENOSINE KINASE)	2ba0	ARCHAEAL EXOSOME RNA BINDING PROTEIN RRP4 (Archaeoglobus fulgidus)	4 / 4	ASN A 90 LEU A 85 SER A 88 LEU A 114	None	1.10A	5kb5A-2ba0A: undetectable	5kb5A-2ba0A: 20.05

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RX3_A_MTXA161_2","DIHYDROFOLATE REDUCTASE","2ba0","ARCHAEAL EXOSOME RNA BINDING PROTEIN RRP4","Archaeoglobus fulgidus",3,"LYS A   2;ILE A  34;THR A  22","None","0.80A","1rx3A-2ba0A:undetectable","1rx3A-2ba0A:21.90"],["4GH8_A_MTXA201_2","DIHYDROFOLATE REDUCTASE","2ba0","ARCHAEAL EXOSOME RNA BINDING PROTEIN RRP4","Archaeoglobus fulgidus",3,"LYS A   2;ILE A  34;THR A  22","None","0.86A","4gh8A-2ba0A:undetectable","4gh8A-2ba0A:21.49"],["4N09_C_ADNC401_2","ADENOSINE KINASE","2ba0","ARCHAEAL EXOSOME RNA BINDING PROTEIN RRP4","Archaeoglobus fulgidus",4,"ASN A  90;LEU A  85;SER A  88;LEU A 114","None","1.14A","4n09C-2ba0A:undetectable","4n09C-2ba0A:19.72"],["5EML_A_SAMA701_1","PROTEIN ARGININE N-METHYLTRANSFERASE 5","2ba0","ARCHAEAL EXOSOME RNA BINDING PROTEIN RRP4","Archaeoglobus fulgidus",4,"TYR A  53;TYR A  20;GLY A  58;ASP A 128","None","1.04A","5emlA-2ba0A:undetectable","5emlA-2ba0A:15.54"],["5KB5_A_ADNA401_2","ADENOSINE KINASE","2ba0","ARCHAEAL EXOSOME RNA BINDING PROTEIN RRP4","Archaeoglobus fulgidus",4,"ASN A  90;LEU A  85;SER A  88;LEU A 114","None","1.10A","5kb5A-2ba0A:undetectable","5kb5A-2ba0A:20.05"]]