SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bac'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_2
(PROTEIN (HIV-1
PROTEASE))		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		5 / 8 LEU A 418
ALA A  17
GLY A  13
ILE A  35
PHE A 397
 None
FAD  A 500 (-3.1A)
FAD  A 500 (-3.2A)
None
None
 1.32A 1d4sB-2bacA:
undetectable		 1d4sB-2bacA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		3 / 3 TRP A 199
VAL A  64
PRO A  65
 None
ODT  A1001 ( 4.4A)
None
 0.71A 1rg1A-2bacA:
undetectable		 1rg1A-2bacA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		3 / 3 TRP A 199
VAL A  64
PRO A  65
 None
ODT  A1001 ( 4.4A)
None
 0.71A 1rh0A-2bacA:
undetectable		 1rh0A-2bacA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 7 ARG A  54
ASP A 319
THR A 200
GLY A  83
 None
 0.96A 2f6dA-2bacA:
undetectable		 2f6dA-2bacA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 6 TYR A 180
GLY A 132
TYR A 379
ASN A 131
 None
 1.19A 2g72A-2bacA:
undetectable		 2g72A-2bacA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 4 VAL A  64
PHE A 168
VAL A 181
TRP A 161
 ODT  A1001 ( 4.4A)
ODT  A1001 (-3.7A)
None
None
 1.36A 2y00A-2bacA:
0.0		 2y00A-2bacA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YS6_A_GLYA431_0
(PHOSPHORIBOSYLGLYCIN
AMIDE SYNTHETASE)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 8 ASP A 417
TYR A 134
ASN A 135
GLY A 132
 None
 0.70A 2ys6A-2bacA:
3.0		 2ys6A-2bacA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_1
(PROTEASE)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		5 / 8 LEU A 418
GLY A  22
VAL A 411
GLY A  13
ILE A  12
 None
None
FAD  A 500 ( 4.3A)
FAD  A 500 (-3.2A)
FAD  A 500 ( 4.8A)
 1.06A 3ekpA-2bacA:
undetectable		 3ekpA-2bacA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		5 / 8 TYR A 281
TYR A 370
GLY A  44
THR A 205
ILE A  61
 FAD  A 500 ( 4.6A)
FAD  A 500 ( 4.5A)
FAD  A 500 (-3.5A)
None
FAD  A 500 (-4.5A)
 1.46A 3jusB-2bacA:
undetectable		 3jusB-2bacA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		5 / 9 TYR A 281
TYR A 370
GLY A  44
THR A 205
ILE A  61
 FAD  A 500 ( 4.6A)
FAD  A 500 ( 4.5A)
FAD  A 500 (-3.5A)
None
FAD  A 500 (-4.5A)
 1.46A 3jusB-2bacA:
undetectable		 3jusB-2bacA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_B_ECNB411_1
(FLAVOHEMOGLOBIN)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		5 / 9 ILE A 229
TYR A 262
ALA A  10
LEU A 250
ALA A 265
 None
FAD  A 500 (-4.4A)
None
None
None
 1.10A 3ozvB-2bacA:
undetectable		 3ozvB-2bacA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S68_A_SAMA228_1
(CATECHOL
O-METHYLTRANSFERASE)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		5 / 12 VAL A 176
TYR A 180
ASN A 152
ALA A 113
PHE A 165
 None
 1.27A 3s68A-2bacA:
2.4		 3s68A-2bacA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 8 VAL A 181
LEU A 185
ILE A 162
MET A 302
 None
 0.83A 3u5kA-2bacA:
undetectable		 3u5kA-2bacA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 8 VAL A 181
LEU A 185
ILE A 162
MET A 302
 None
 0.92A 3u5kD-2bacA:
undetectable		 3u5kD-2bacA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 8 PHE A 168
GLY A 169
GLY A 296
MET A  62
 ODT  A1001 (-3.7A)
None
None
ODT  A1001 ( 3.9A)
 0.87A 3v3nB-2bacA:
16.1		 3v3nB-2bacA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 8 PHE A 168
GLY A 169
GLY A 296
MET A  62
 ODT  A1001 (-3.7A)
None
None
ODT  A1001 ( 3.9A)
 0.87A 3v3nC-2bacA:
16.0		 3v3nC-2bacA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 5 GLU A  57
GLY A  59
TYR A  56
GLU A 364
 None
FAD  A 500 (-3.5A)
None
None
 1.30A 3w9tA-2bacA:
undetectable		 3w9tA-2bacA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 5 GLU A  57
GLY A  59
TYR A  56
GLU A 364
 None
FAD  A 500 (-3.5A)
None
None
 1.31A 3w9tC-2bacA:
undetectable		 3w9tC-2bacA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 5 GLU A  57
GLY A  59
TYR A  56
GLU A 364
 None
FAD  A 500 (-3.5A)
None
None
 1.30A 3w9tD-2bacA:
undetectable		 3w9tD-2bacA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 5 GLU A  57
GLY A  59
TYR A  56
GLU A 364
 None
FAD  A 500 (-3.5A)
None
None
 1.29A 3w9tG-2bacA:
undetectable		 3w9tG-2bacA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		5 / 11 GLY A  18
ALA A  17
PRO A 372
ILE A 402
LEU A 256
 None
FAD  A 500 (-3.1A)
None
None
None
 1.08A 4dt8A-2bacA:
undetectable		 4dt8A-2bacA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB203_1
(CALMODULIN)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 7 PHE A 209
LEU A 212
MET A  23
ALA A  21
 None
 1.00A 4rjdB-2bacA:
undetectable		 4rjdB-2bacA:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZC_D_EF2D505_1
(PROTEIN CEREBLON)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 8 TYR A  67
THR A 189
HIS A 413
PHE A 209
 FAD  A 500 ( 4.8A)
None
None
None
 1.46A 4tzcB-2bacA:
undetectable
4tzcD-2bacA:
undetectable		 4tzcB-2bacA:
11.69
4tzcD-2bacA:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 8 MET A 190
ALA A 113
LEU A 117
GLY A 118
 None
 1.01A 4xk8a-2bacA:
undetectable		 4xk8a-2bacA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 6 ALA A 285
THR A 326
VAL A 283
TYR A 328
 None
None
None
ODT  A1001 ( 4.0A)
 1.03A 5eclA-2bacA:
undetectable		 5eclA-2bacA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 8 ALA A 285
THR A 326
VAL A 283
TYR A 328
 None
None
None
ODT  A1001 ( 4.0A)
 0.87A 5ecnD-2bacA:
undetectable		 5ecnD-2bacA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		5 / 12 ALA A  20
GLY A  13
ALA A  21
THR A 253
ILE A  11
 None
FAD  A 500 (-3.2A)
None
None
None
 1.04A 5eeuI-2bacA:
undetectable
5eeuJ-2bacA:
undetectable		 5eeuI-2bacA:
11.58
5eeuJ-2bacA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		5 / 12 ALA A  20
GLY A  13
ALA A  21
THR A 253
ILE A  11
 None
FAD  A 500 (-3.2A)
None
None
None
 1.04A 5eevI-2bacA:
undetectable
5eevJ-2bacA:
undetectable		 5eevI-2bacA:
11.58
5eevJ-2bacA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		5 / 12 ALA A  20
GLY A  13
ALA A  21
THR A 253
ILE A  11
 None
FAD  A 500 (-3.2A)
None
None
None
 1.04A 5eewI-2bacA:
undetectable
5eewJ-2bacA:
undetectable		 5eewI-2bacA:
11.58
5eewJ-2bacA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHQ_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		5 / 12 VAL A 176
TYR A 180
ASN A 152
ALA A 113
ASP A 159
 None
 1.20A 5fhqA-2bacA:
0.0		 5fhqA-2bacA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_2
(ESTROGEN RECEPTOR)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 6 LEU A 151
LEU A 117
LEU A 120
LEU A 141
 None
 0.84A 5gs4A-2bacA:
undetectable		 5gs4A-2bacA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_2
(PROTEASE E35D-APV)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		5 / 9 LEU A 418
GLY A  22
VAL A 411
GLY A  13
ILE A  12
 None
None
FAD  A 500 ( 4.3A)
FAD  A 500 (-3.2A)
FAD  A 500 ( 4.8A)
 1.04A 5kr0B-2bacA:
undetectable		 5kr0B-2bacA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		3 / 3 ASN A 407
TYR A  67
CYH A 412
 FAD  A 500 (-4.2A)
FAD  A 500 ( 4.8A)
None
 1.02A 5lsuB-2bacA:
undetectable		 5lsuB-2bacA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F8C_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 6 ALA A 318
GLY A  83
THR A 200
ILE A  61
 None
None
None
FAD  A 500 (-4.5A)
 0.85A 6f8cA-2bacA:
undetectable		 6f8cA-2bacA:
12.68