SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bas'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HTH_A_PRLA201_0
(EBRA REPRESSOR)		 2bas YKUI PROTEIN
(Bacillus
subtilis) 		5 / 9 PHE A 365
VAL A 268
LEU A 400
TYR A 369
ASP A 394
 None
 0.98A 3hthA-2basA:
0.7		 3hthA-2basA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 2bas YKUI PROTEIN
(Bacillus
subtilis) 		6 / 12 TYR A 219
TYR A 188
GLY A 155
ASN A 153
ALA A 199
LEU A 206
 None
 1.50A 3vywA-2basA:
undetectable		 3vywA-2basA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 2bas YKUI PROTEIN
(Bacillus
subtilis) 		5 / 8 GLY A 319
GLN A 321
SER A 345
PHE A 350
ASN A 343
 None
 1.15A 4wryA-2basA:
undetectable		 4wryA-2basA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 2bas YKUI PROTEIN
(Bacillus
subtilis) 		5 / 8 GLY A 319
GLN A 321
SER A 345
PHE A 350
ASN A 343
 None
 1.16A 4wrzA-2basA:
undetectable		 4wrzA-2basA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 2bas YKUI PROTEIN
(Bacillus
subtilis) 		4 / 7 GLN A 321
SER A 345
PHE A 350
ASN A 343
 None
 1.07A 4ws0A-2basA:
undetectable		 4ws0A-2basA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 2bas YKUI PROTEIN
(Bacillus
subtilis) 		4 / 7 GLY A 319
SER A 345
PHE A 350
ASN A 343
 None
 1.03A 4ws0A-2basA:
undetectable		 4ws0A-2basA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 2bas YKUI PROTEIN
(Bacillus
subtilis) 		4 / 8 GLY A 319
SER A 345
PHE A 350
ASN A 343
 None
 1.00A 4ws1A-2basA:
undetectable		 4ws1A-2basA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_B_DB8B800_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 2bas YKUI PROTEIN
(Bacillus
subtilis) 		5 / 10 ALA A 165
ILE A 202
LEU A 172
ALA A 204
ASP A 170
 None
 1.33A 5ajqB-2basA:
undetectable		 5ajqB-2basA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 2bas YKUI PROTEIN
(Bacillus
subtilis) 		5 / 10 GLY A 146
LEU A 116
LEU A 103
TYR A 141
TYR A 142
 None
 1.29A 5hwkA-2basA:
undetectable		 5hwkA-2basA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 2bas YKUI PROTEIN
(Bacillus
subtilis) 		5 / 10 GLY A 146
LEU A 116
LEU A 103
TYR A 141
TYR A 142
 None
 1.29A 5hwkB-2basA:
undetectable		 5hwkB-2basA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 2bas YKUI PROTEIN
(Bacillus
subtilis) 		5 / 12 ASP A 367
LEU A 206
LEU A 192
SER A 185
ARG A 200
 None
 1.17A 5nd7B-2basA:
undetectable		 5nd7B-2basA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWV_A_BEZA202_0
(ARA H 8 ALLERGEN)		 2bas YKUI PROTEIN
(Bacillus
subtilis) 		4 / 4 PHE A 297
ASP A 296
LEU A 301
LYS A 300
 None
 1.46A 6awvA-2basA:
undetectable		 6awvA-2basA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 2bas YKUI PROTEIN
(Bacillus
subtilis) 		3 / 3 ARG A 361
LYS A 362
ARG A 278
 None
 1.24A 6c06D-2basA:
undetectable		 6c06D-2basA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2bas YKUI PROTEIN
(Bacillus
subtilis) 		4 / 7 ALA A 302
THR A 306
GLN A 336
VAL A 326
 None
 0.96A 6cduA-2basA:
undetectable
6cduE-2basA:
undetectable		 6cduA-2basA:
21.62
6cduE-2basA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_B_EY4B500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2bas YKUI PROTEIN
(Bacillus
subtilis) 		4 / 6 GLN A 336
VAL A 326
ALA A 302
THR A 306
 None
 1.03A 6cduB-2basA:
undetectable
6cduC-2basA:
undetectable		 6cduB-2basA:
21.62
6cduC-2basA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2bas YKUI PROTEIN
(Bacillus
subtilis) 		5 / 8 ILE A 334
GLN A 336
VAL A 326
ALA A 302
THR A 306
 None
 1.29A 6cduD-2basA:
undetectable
6cduE-2basA:
undetectable		 6cduD-2basA:
21.62
6cduE-2basA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2bas YKUI PROTEIN
(Bacillus
subtilis) 		5 / 7 ALA A 302
THR A 306
ILE A 334
GLN A 336
VAL A 326
 None
 1.23A 6cduF-2basA:
undetectable
6cduJ-2basA:
undetectable		 6cduF-2basA:
21.62
6cduJ-2basA:
21.62