SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bb2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 2bb2 BETA B2-CRYSTALLIN
(Bos
taurus) 		4 / 5 VAL A  43
GLY A  44
VAL A  56
TRP A  68
 None
 1.13A 1tkqB-2bb2A:
undetectable		 1tkqB-2bb2A:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA304_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 2bb2 BETA B2-CRYSTALLIN
(Bos
taurus) 		4 / 4 GLN A 163
PRO A 162
VAL A 121
GLU A  94
 None
 1.09A 3huoA-2bb2A:
undetectable		 3huoA-2bb2A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 2bb2 BETA B2-CRYSTALLIN
(Bos
taurus) 		5 / 10 TYR A  62
PHE A  57
VAL A  37
GLY A  60
GLY A  40
 None
 1.31A 3km6A-2bb2A:
undetectable		 3km6A-2bb2A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 2bb2 BETA B2-CRYSTALLIN
(Bos
taurus) 		3 / 3 ASP A 108
ARG A 168
ASP A 106
 None
 0.89A 4fp9F-2bb2A:
undetectable		 4fp9F-2bb2A:
19.38