SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bba'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)		 2bba EPHRIN TYPE-B
RECEPTOR 4
(Homo
sapiens) 		3 / 3 PHE A 178
LEU A  90
LEU A 164
 None
 0.67A 1mx1E-2bbaA:
undetectable		 1mx1E-2bbaA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_A_9PLA501_1
(CYTOCHROME P450 2E1)		 2bba EPHRIN TYPE-B
RECEPTOR 4
(Homo
sapiens) 		4 / 6 PHE A 178
ALA A 177
THR A  75
LEU A 166
 None
 0.77A 3t3zA-2bbaA:
undetectable		 3t3zA-2bbaA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_B_9PLB501_1
(CYTOCHROME P450 2E1)		 2bba EPHRIN TYPE-B
RECEPTOR 4
(Homo
sapiens) 		4 / 6 PHE A 178
ALA A 177
THR A  75
LEU A 166
 None
 0.78A 3t3zB-2bbaA:
undetectable		 3t3zB-2bbaA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 2bba EPHRIN TYPE-B
RECEPTOR 4
(Homo
sapiens) 		4 / 5 PHE A 178
ALA A 177
THR A  75
LEU A 166
 None
 0.80A 3t3zC-2bbaA:
undetectable		 3t3zC-2bbaA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_D_9PLD501_1
(CYTOCHROME P450 2E1)		 2bba EPHRIN TYPE-B
RECEPTOR 4
(Homo
sapiens) 		4 / 6 PHE A 178
ALA A 177
THR A  75
LEU A 166
 None
 0.79A 3t3zD-2bbaA:
undetectable		 3t3zD-2bbaA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_B_CHDB102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2bba EPHRIN TYPE-B
RECEPTOR 4
(Homo
sapiens) 		5 / 11 LEU A 166
LEU A 192
ALA A 177
LEU A 176
TYR A 115
 None
 1.17A 4wg0B-2bbaA:
undetectable
4wg0C-2bbaA:
undetectable
4wg0D-2bbaA:
undetectable		 4wg0B-2bbaA:
4.86
4wg0C-2bbaA:
4.86
4wg0D-2bbaA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_D_CHDD102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2bba EPHRIN TYPE-B
RECEPTOR 4
(Homo
sapiens) 		5 / 11 LEU A 166
LEU A 192
ALA A 177
LEU A 176
TYR A 115
 None
 1.19A 4wg0D-2bbaA:
undetectable
4wg0E-2bbaA:
undetectable
4wg0F-2bbaA:
undetectable		 4wg0D-2bbaA:
4.86
4wg0E-2bbaA:
4.86
4wg0F-2bbaA:
4.86