SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bbe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_A_SAMA105_0
(PROTEIN (MET
REPRESSOR))		 2bbe HYPOTHETICAL PROTEIN
SO0527
(Shewanella
oneidensis) 		4 / 8 GLU A  58
ARG A  60
LEU A  21
GLU A  96
 None
 0.95A 1cmaA-2bbeA:
undetectable
1cmaB-2bbeA:
undetectable		 1cmaA-2bbeA:
19.63
1cmaB-2bbeA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRL_B_DOLB301_1
(STREPTOGRAMIN A
ACETYLTRANSFERASE)		 2bbe HYPOTHETICAL PROTEIN
SO0527
(Shewanella
oneidensis) 		5 / 12 TYR A  86
ILE A  83
LEU A  52
PRO A  39
VAL A  54
 None
 1.10A 1mrlB-2bbeA:
0.0
1mrlC-2bbeA:
0.0		 1mrlB-2bbeA:
19.32
1mrlC-2bbeA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 2bbe HYPOTHETICAL PROTEIN
SO0527
(Shewanella
oneidensis) 		4 / 7 TYR A  50
GLU A  66
HIS A  77
TYR A  86
 None
 0.78A 1tuvA-2bbeA:
14.0		 1tuvA-2bbeA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 2bbe HYPOTHETICAL PROTEIN
SO0527
(Shewanella
oneidensis) 		5 / 11 TYR A  86
PHE A  87
TYR A  50
LEU A  52
ILE A  38
 None
 1.25A 1yatA-2bbeA:
undetectable		 1yatA-2bbeA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLA_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2bbe HYPOTHETICAL PROTEIN
SO0527
(Shewanella
oneidensis) 		4 / 8 LEU A  37
LEU A  34
LEU A  30
ILE A  83
 None
 0.83A 4klaA-2bbeA:
undetectable		 4klaA-2bbeA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_K_PACK1_0
(SERINE PROTEASE NS3
PEPTIDE
PAC-DLY-DLY-DAR)		 2bbe HYPOTHETICAL PROTEIN
SO0527
(Shewanella
oneidensis) 		3 / 3 ALA A  35
VAL A  90
TYR A  86
 None
 0.69A 5zmqH-2bbeA:
undetectable		 5zmqH-2bbeA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 2bbe HYPOTHETICAL PROTEIN
SO0527
(Shewanella
oneidensis) 		4 / 7 PHE A  68
ILE A  14
CYH A  16
ILE A  83
 None
 0.85A 6b5vA-2bbeA:
undetectable
6b5vC-2bbeA:
undetectable		 6b5vA-2bbeA:
15.74
6b5vC-2bbeA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 2bbe HYPOTHETICAL PROTEIN
SO0527
(Shewanella
oneidensis) 		4 / 7 PHE A  68
ILE A  14
CYH A  16
ILE A  83
 None
 0.85A 6b5vA-2bbeA:
undetectable
6b5vB-2bbeA:
undetectable		 6b5vA-2bbeA:
15.74
6b5vB-2bbeA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 2bbe HYPOTHETICAL PROTEIN
SO0527
(Shewanella
oneidensis) 		4 / 7 PHE A  68
ILE A  14
CYH A  16
ILE A  83
 None
 0.85A 6b5vC-2bbeA:
undetectable
6b5vD-2bbeA:
undetectable		 6b5vC-2bbeA:
15.74
6b5vD-2bbeA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 2bbe HYPOTHETICAL PROTEIN
SO0527
(Shewanella
oneidensis) 		4 / 7 PHE A  68
ILE A  14
CYH A  16
ILE A  83
 None
 0.85A 6b5vB-2bbeA:
undetectable
6b5vD-2bbeA:
undetectable		 6b5vB-2bbeA:
15.74
6b5vD-2bbeA:
15.74