SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bcc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE
(Gallus
gallus) 		6 / 12 ILE A 116
CYH A 120
GLN A  72
PHE A  64
LEU A  75
VAL A  39
 None
 1.43A 1fbyA-2bccA:
undetectable		 1fbyA-2bccA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE
(Gallus
gallus) 		6 / 12 ILE A 116
CYH A 120
GLN A  72
PHE A  64
LEU A  75
VAL A  39
 None
 1.46A 1fbyB-2bccA:
undetectable		 1fbyB-2bccA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE
(Gallus
gallus) 		4 / 6 ALA A 423
SER A 330
TRP A 342
LEU A 153
 None
 1.14A 1gahA-2bccA:
undetectable		 1gahA-2bccA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_1
(LIVER
CARBOXYLESTERASE I)		 2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE
(Gallus
gallus) 		5 / 12 GLY A  56
LEU A 182
LEU A 177
LEU A 186
HIS A 189
 None
 0.94A 1mx1D-2bccA:
undetectable		 1mx1D-2bccA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE
(Gallus
gallus) 		3 / 3 ASP A 132
ARG A 175
ARG A 131
 None
 1.04A 2j9dA-2bccA:
3.5
2j9dC-2bccA:
2.5		 2j9dA-2bccA:
14.50
2j9dC-2bccA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_A_LYAA1270_2
(PTERIDINE REDUCTASE)		 2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE
(Gallus
gallus) 		3 / 3 MET A 343
VAL A 354
GLU A 409
 None
 0.66A 2x9gA-2bccA:
undetectable		 2x9gA-2bccA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_B_SALB1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE
(Gallus
gallus) 		5 / 10 ILE A 255
GLY A 321
PHE A 320
PRO A 420
ILE A 415
 None
 1.40A 2y7wB-2bccA:
undetectable		 2y7wB-2bccA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)		 2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE
(Gallus
gallus) 		3 / 3 MET A 334
MET A 343
PHE A 307
 None
 1.22A 3gn8A-2bccA:
undetectable		 3gn8A-2bccA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_B_VORB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE
(Gallus
gallus) 		5 / 11 LEU A 345
VAL A 410
ILE A 276
ALA A 269
ALA A 275
 None
 1.07A 3mdtB-2bccA:
undetectable		 3mdtB-2bccA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA803_1
(CATALASE-PEROXIDASE)		 2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE
(Gallus
gallus) 		4 / 4 ASP A  42
THR A 385
VAL A 228
SER A 315
 None
 1.50A 3wxoA-2bccA:
1.0		 3wxoA-2bccA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE
(Gallus
gallus) 		5 / 12 GLY A  38
THR A  95
ALA A 114
VAL A 117
VAL A  37
 None
 1.49A 4df3A-2bccA:
undetectable		 4df3A-2bccA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE
(Gallus
gallus) 		5 / 12 GLY A  38
THR A  95
ALA A 114
VAL A 117
VAL A  37
 None
 1.50A 4df3B-2bccA:
undetectable		 4df3B-2bccA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE
(Gallus
gallus) 		5 / 12 GLY A 259
PRO A 260
GLY A 261
THR A 156
LEU A 153
 None
 0.86A 4n48A-2bccA:
undetectable		 4n48A-2bccA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE
(Gallus
gallus) 		5 / 12 GLY A 259
PRO A 260
GLY A 261
THR A 156
LEU A 153
 None
 0.91A 4n49A-2bccA:
undetectable		 4n49A-2bccA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE
(Gallus
gallus) 		4 / 5 ILE A 134
ASP A 142
GLU A 137
VAL A 167
 None
 1.07A 4nkxC-2bccA:
undetectable		 4nkxC-2bccA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE
(Gallus
gallus) 		4 / 5 ILE A 134
ASP A 142
GLU A 137
VAL A 167
 None
 1.11A 4nkxD-2bccA:
undetectable		 4nkxD-2bccA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)		 2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE
(Gallus
gallus) 		4 / 7 GLY A 340
GLY A 440
SER A 439
LEU A 444
 None
 0.82A 5izfA-2bccA:
undetectable		 5izfA-2bccA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE
(Gallus
gallus) 		5 / 12 SER A  81
VAL A  79
ALA A 101
ALA A  84
GLY A  83
 None
 1.24A 5tzoA-2bccA:
undetectable		 5tzoA-2bccA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE
(Gallus
gallus) 		5 / 12 SER A  81
VAL A  79
ALA A 101
ALA A  84
GLY A  83
 None
 1.22A 5tzoC-2bccA:
undetectable		 5tzoC-2bccA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA612_1
(SERUM ALBUMIN)		 2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE
(Gallus
gallus) 		5 / 12 GLU A 130
LEU A 186
LEU A 122
ILE A 116
ALA A  63
 None
 1.18A 5v0vA-2bccA:
undetectable		 5v0vA-2bccA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_1
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE
(Gallus
gallus) 		4 / 6 ARG A 244
ARG A 242
ASP A 246
ASP A 332
 None
 1.26A 5zw4A-2bccA:
undetectable		 5zw4A-2bccA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE
(Gallus
gallus) 		4 / 6 PHE A 336
ILE A 297
ASN A 301
ASP A 333
 None
 1.17A 6dhbA-2bccA:
undetectable		 6dhbA-2bccA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE
(Gallus
gallus) 		4 / 7 LEU A 431
ASP A 433
ARG A 242
GLN A 339
 None
 1.42A 6g31D-2bccA:
undetectable		 6g31D-2bccA:
12.26