SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bd0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQU_A_EQIA329_0
(PROTEIN (ESTRADIOL
17
BETA-DEHYDROGENASE
1))		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		5 / 10 SER A 145
VAL A 146
TYR A 158
GLY A 189
ARG A 235
 NAP  A 800 (-3.4A)
None
None
NAP  A 800 (-4.7A)
None
 0.99A 1equA-2bd0A:
28.5		 1equA-2bd0A:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		5 / 12 GLY A   9
ARG A  41
ASP A  66
SER A  68
ALA A  94
 NAP  A 800 (-3.2A)
NAP  A 800 (-3.4A)
NAP  A 800 (-3.6A)
NAP  A 800 ( 4.1A)
NAP  A 800 (-3.6A)
 0.91A 2br4C-2bd0A:
7.0		 2br4C-2bd0A:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		4 / 6 ARG A  41
ASP A 109
THR A 106
ASP A 104
 NAP  A 800 (-3.4A)
None
None
None
 1.24A 2okcB-2bd0A:
6.0		 2okcB-2bd0A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		5 / 12 ILE A  18
ALA A  17
GLY A  13
ILE A 213
GLY A   9
 None
None
NAP  A 800 (-3.5A)
None
NAP  A 800 (-3.2A)
 0.99A 2qe6B-2bd0A:
6.5		 2qe6B-2bd0A:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		5 / 10 ILE A  18
TYR A 221
LEU A  36
VAL A  37
LEU A  38
 None
 1.41A 2w98A-2bd0A:
7.4		 2w98A-2bd0A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		5 / 7 PHE A  32
ALA A  26
ALA A  58
THR A  60
LEU A  38
 None
 1.34A 2wx2A-2bd0A:
undetectable		 2wx2A-2bd0A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_A_ADNA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		5 / 10 ILE A   7
ASN A  93
ALA A  94
VAL A  37
LEU A  46
 None
NAP  A 800 (-3.4A)
NAP  A 800 (-3.6A)
None
None
 1.38A 3ay0A-2bd0A:
6.1		 3ay0A-2bd0A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_P_TRPP1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		4 / 7 GLY A 189
VAL A 146
ASP A 240
ILE A 241
 NAP  A 800 (-4.7A)
None
None
None
 0.93A 3fi0P-2bd0A:
undetectable		 3fi0P-2bd0A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		5 / 11 ARG A  24
GLN A 223
VAL A 229
ILE A  18
PRO A 188
 None
None
None
None
NAP  A 800 (-3.7A)
 1.50A 3ganA-2bd0A:
undetectable		 3ganA-2bd0A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		3 / 3 ALA A  17
ARG A  16
LYS A  48
 None
 0.97A 3kp3B-2bd0A:
undetectable		 3kp3B-2bd0A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		3 / 3 GLU A  33
LEU A  59
LEU A  20
 None
 0.70A 3ohtA-2bd0A:
undetectable		 3ohtA-2bd0A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_2
(P38A)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		3 / 3 GLU A  33
LEU A  59
LEU A  20
 None
 0.70A 3ohtB-2bd0A:
undetectable		 3ohtB-2bd0A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHN_A_ACTA108_0
(PROTEIN P-30)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		3 / 3 THR A 116
SER A  68
ARG A  41
 NAP  A 800 (-3.0A)
NAP  A 800 ( 4.1A)
NAP  A 800 (-3.4A)
 0.67A 3phnA-2bd0A:
undetectable		 3phnA-2bd0A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		5 / 11 ILE A 143
ILE A 213
ALA A  19
GLU A  21
VAL A  91
 NAP  A 800 (-4.3A)
None
None
None
None
 1.07A 3tmzA-2bd0A:
undetectable		 3tmzA-2bd0A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		3 / 3 PHE A 141
CYH A  89
HIS A 139
 None
 0.78A 3u9fF-2bd0A:
undetectable		 3u9fF-2bd0A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		3 / 3 PHE A 141
CYH A  89
HIS A 139
 None
 0.85A 3u9fG-2bd0A:
undetectable		 3u9fG-2bd0A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		3 / 3 PHE A 141
CYH A  89
HIS A 139
 None
 0.91A 3u9fL-2bd0A:
undetectable		 3u9fL-2bd0A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		3 / 3 PHE A 141
CYH A  89
HIS A 139
 None
 0.89A 3u9fS-2bd0A:
undetectable		 3u9fS-2bd0A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BKJ_B_STIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		4 / 5 LEU A   6
TYR A 175
MET A 172
ARG A  75
 None
 1.47A 4bkjB-2bd0A:
undetectable		 4bkjB-2bd0A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		5 / 12 GLY A  15
GLY A  13
ILE A  49
VAL A  91
VAL A 217
 None
NAP  A 800 (-3.5A)
None
None
None
 0.97A 4gc9A-2bd0A:
5.4		 4gc9A-2bd0A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		4 / 8 PHE A  99
SER A 161
ALA A 147
SER A 145
 None
None
None
NAP  A 800 (-3.4A)
 1.14A 4lv9A-2bd0A:
undetectable
4lv9B-2bd0A:
undetectable		 4lv9A-2bd0A:
19.57
4lv9B-2bd0A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		4 / 7 PHE A  99
SER A 161
ALA A 147
SER A 145
 None
None
None
NAP  A 800 (-3.4A)
 1.10A 4lv9A-2bd0A:
undetectable
4lv9B-2bd0A:
undetectable		 4lv9A-2bd0A:
19.57
4lv9B-2bd0A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		6 / 12 ALA A  26
PHE A  32
ILE A   4
ALA A  58
THR A  60
ALA A  19
 None
 1.43A 4nkxB-2bd0A:
undetectable		 4nkxB-2bd0A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EQB_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		5 / 12 ILE A  49
GLY A  11
GLY A   9
LEU A   6
THR A  78
 None
NAP  A 800 (-3.9A)
NAP  A 800 (-3.2A)
None
None
 1.03A 5eqbA-2bd0A:
undetectable		 5eqbA-2bd0A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		4 / 7 ILE A  87
THR A   8
PHE A  22
LEU A 128
 None
 0.63A 5fukA-2bd0A:
0.0
5fukB-2bd0A:
0.0		 5fukA-2bd0A:
22.30
5fukB-2bd0A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		5 / 11 CYH A  53
ALA A  17
GLY A  15
ALA A  10
LEU A  76
 None
 1.12A 5lf7H-2bd0A:
undetectable
5lf7I-2bd0A:
undetectable		 5lf7H-2bd0A:
21.30
5lf7I-2bd0A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 2bd0 SEPIAPTERIN
REDUCTASE
(Chlorobaculum
tepidum) 		5 / 11 CYH A  53
ALA A  17
GLY A  15
ALA A  10
LEU A  76
 None
 1.11A 5lf7V-2bd0A:
undetectable
5lf7W-2bd0A:
undetectable		 5lf7V-2bd0A:
21.30
5lf7W-2bd0A:
21.69