SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bdq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 2bdq COPPER HOMEOSTASIS
PROTEIN CUTC
(Streptococcus
agalactiae) 		5 / 10 ALA A 115
GLU A  79
LEU A  83
ARG A  76
ILE A  43
 None
 1.46A 1a52A-2bdqA:
undetectable		 1a52A-2bdqA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 2bdq COPPER HOMEOSTASIS
PROTEIN CUTC
(Streptococcus
agalactiae) 		5 / 10 ALA A 115
MET A  78
ARG A  76
ILE A  97
LEU A 121
 None
 1.46A 1a52A-2bdqA:
undetectable		 1a52A-2bdqA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 2bdq COPPER HOMEOSTASIS
PROTEIN CUTC
(Streptococcus
agalactiae) 		5 / 10 ALA A 115
MET A  78
ARG A  76
ILE A  97
LEU A 121
 None
 1.44A 1a52B-2bdqA:
undetectable		 1a52B-2bdqA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)		 2bdq COPPER HOMEOSTASIS
PROTEIN CUTC
(Streptococcus
agalactiae) 		4 / 8 ALA A  46
LEU A  14
LEU A  27
ALA A   8
 None
 0.77A 1e7cA-2bdqA:
undetectable		 1e7cA-2bdqA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DLC_A_SAMA220_0
(PUTATIVE
S-ADENOSYL-L-METHION
INE-DEPENDENT
METHYLTRANSFERASE)		 2bdq COPPER HOMEOSTASIS
PROTEIN CUTC
(Streptococcus
agalactiae) 		5 / 12 TYR A 192
ASP A  91
VAL A  57
HIS A  51
ARG A   4
 None
 1.40A 3dlcA-2bdqA:
undetectable		 3dlcA-2bdqA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_C_PM6C1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2bdq COPPER HOMEOSTASIS
PROTEIN CUTC
(Streptococcus
agalactiae) 		4 / 6 GLU A   5
THR A 148
ALA A  58
ALA A  92
 None
 0.99A 3ns1C-2bdqA:
undetectable		 3ns1C-2bdqA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_A_8PRA601_1
(RHODOPSIN KINASE)		 2bdq COPPER HOMEOSTASIS
PROTEIN CUTC
(Streptococcus
agalactiae) 		4 / 7 ALA A  58
LEU A  17
MET A  60
ASP A  29
 None
 0.82A 4l9iA-2bdqA:
undetectable		 4l9iA-2bdqA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 2bdq COPPER HOMEOSTASIS
PROTEIN CUTC
(Streptococcus
agalactiae) 		4 / 8 GLY A 158
GLY A 185
ILE A 161
LEU A 152
 None
 0.78A 4mwzB-2bdqA:
undetectable		 4mwzB-2bdqA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 2bdq COPPER HOMEOSTASIS
PROTEIN CUTC
(Streptococcus
agalactiae) 		4 / 7 LEU A  11
ILE A  22
ILE A  55
VAL A  25
 None
 0.83A 4ojbA-2bdqA:
undetectable		 4ojbA-2bdqA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 2bdq COPPER HOMEOSTASIS
PROTEIN CUTC
(Streptococcus
agalactiae) 		4 / 7 LEU A  73
ASN A  71
LEU A 112
ILE A  97
 None
 1.01A 4okwA-2bdqA:
undetectable		 4okwA-2bdqA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UW0_A_SAMA1506_0
(WBDD)		 2bdq COPPER HOMEOSTASIS
PROTEIN CUTC
(Streptococcus
agalactiae) 		5 / 12 ALA A  92
ILE A  55
LEU A  27
VAL A  25
ILE A  22
 None
 1.06A 4uw0A-2bdqA:
3.2		 4uw0A-2bdqA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 2bdq COPPER HOMEOSTASIS
PROTEIN CUTC
(Streptococcus
agalactiae) 		5 / 10 GLY A 185
ALA A 204
VAL A 187
GLU A   5
ILE A 161
 None
 1.13A 5i3cB-2bdqA:
undetectable		 5i3cB-2bdqA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 2bdq COPPER HOMEOSTASIS
PROTEIN CUTC
(Streptococcus
agalactiae) 		5 / 10 ALA A 115
GLU A  79
LEU A  83
ARG A  76
ILE A  43
 None
 1.47A 6cbzB-2bdqA:
undetectable		 6cbzB-2bdqA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 2bdq COPPER HOMEOSTASIS
PROTEIN CUTC
(Streptococcus
agalactiae) 		3 / 3 VAL A  25
GLU A   5
ILE A  55
 None
 0.59A 6f7lB-2bdqA:
undetectable		 6f7lB-2bdqA:
18.12